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- W54764250 abstract "The sleeping rat cycles between two well characterized physiological states, slow-wave sleep (SWS) and rapid eye-movement sleep (REM), often identified by the presence of large irregular (LIA) and theta activity, respectively, in the hippocampal EEG. Inspection of the of ensembles of hippocampal CA1 complex-spike cells along with the EEG reveals the presence of a third physiological state, distinctly different from both REM and SWS in both hippocampal EEG and population activity. The EEG during this state abruptly flattens for a few seconds, appearing very similar to the small-amplitude irregular activity (SIA) hippocampal EEG state reported in the literature to occur when rats are startled out of sleep. The flattening of the EEG is accompanied by a striking pattern of spike in the population of hippocampal pyramidal cells, wherein a small subset of cells becomes very active while the rest become quiet; the same subset of cells is usually active across long sequences of SIA. This dissertation shows (1) that these active cells are place cells whose place fields are in the location in which the rat is sleeping; (2) that the spontaneous SIA observed during sleep corresponds to the SIA state of increased alertness that has been reported in the literature to occur when rats are startled out of sleep; (3) that SIA is accompanied by a desynchronized neocortical EEG and low amplitude EMG; (4) that the cells active in SIA reflect a memory for the location in which the rat fell asleep, rather than an assessment of its location based on current sensory information; and (5) that the generation of SIA is likely to involve an increase of serotonin levels in the medial septal nucleus. It is proposed that SIA serves as a neural substrate for maintaining context memory during sleep, and that it reflects a partial arousal in response to internal or external stimuli that allows the animal to assess whether full awakening is warranted, without disrupting the sleep cycle." @default.
- W54764250 created "2016-06-24" @default.
- W54764250 creator A5047051976 @default.
- W54764250 date "2004-01-16" @default.
- W54764250 modified "2023-09-27" @default.
- W54764250 title "THE SMALL IRREGULAR ACTIVITY STATE IN THE RAT HIPPOCAMPUS" @default.
- W54764250 cites W115176360 @default.
- W54764250 cites W136151004 @default.
- W54764250 cites W1480844456 @default.
- W54764250 cites W1507727310 @default.
- W54764250 cites W1527686769 @default.
- W54764250 cites W1538576000 @default.
- W54764250 cites W1570751785 @default.
- W54764250 cites W1580901834 @default.
- W54764250 cites W1583485127 @default.
- W54764250 cites W1585564530 @default.
- W54764250 cites W1612572634 @default.
- W54764250 cites W1676983329 @default.
- W54764250 cites W1724768868 @default.
- W54764250 cites W178779372 @default.
- W54764250 cites W1840439775 @default.
- W54764250 cites W1842212615 @default.
- W54764250 cites W1857076555 @default.
- W54764250 cites W1898031307 @default.
- W54764250 cites W1917541791 @default.
- W54764250 cites W1927777346 @default.
- W54764250 cites W1950306692 @default.
- W54764250 cites W1953105366 @default.
- W54764250 cites W1964546740 @default.
- W54764250 cites W1964828840 @default.
- W54764250 cites W1965423852 @default.
- W54764250 cites W1965995196 @default.
- W54764250 cites W1966528169 @default.
- W54764250 cites W1968520062 @default.
- W54764250 cites W1969769253 @default.
- W54764250 cites W1972628176 @default.
- W54764250 cites W1972954992 @default.
- W54764250 cites W1973372728 @default.
- W54764250 cites W1974719406 @default.
- W54764250 cites W1976096254 @default.
- W54764250 cites W1976636888 @default.
- W54764250 cites W1978250666 @default.
- W54764250 cites W1983643022 @default.
- W54764250 cites W1984214648 @default.
- W54764250 cites W1984797774 @default.
- W54764250 cites W1985192014 @default.
- W54764250 cites W1987341490 @default.
- W54764250 cites W1987437865 @default.
- W54764250 cites W1987809083 @default.
- W54764250 cites W1988399537 @default.
- W54764250 cites W1988925906 @default.
- W54764250 cites W1989319545 @default.
- W54764250 cites W1990441521 @default.
- W54764250 cites W1990627393 @default.
- W54764250 cites W1991089247 @default.
- W54764250 cites W1991111862 @default.
- W54764250 cites W1991275138 @default.
- W54764250 cites W1992158234 @default.
- W54764250 cites W1993144034 @default.
- W54764250 cites W1993175507 @default.
- W54764250 cites W1993176256 @default.
- W54764250 cites W1993249954 @default.
- W54764250 cites W1993609941 @default.
- W54764250 cites W1994839334 @default.
- W54764250 cites W1995250294 @default.
- W54764250 cites W1995759274 @default.
- W54764250 cites W1998493507 @default.
- W54764250 cites W1998581719 @default.
- W54764250 cites W2000775105 @default.
- W54764250 cites W2001152872 @default.
- W54764250 cites W2002861331 @default.
- W54764250 cites W2003175354 @default.
- W54764250 cites W2003762707 @default.
- W54764250 cites W2004725045 @default.
- W54764250 cites W2006841348 @default.
- W54764250 cites W2007084849 @default.
- W54764250 cites W2008869117 @default.
- W54764250 cites W2012123796 @default.
- W54764250 cites W2016332821 @default.
- W54764250 cites W2016776195 @default.
- W54764250 cites W2018529924 @default.
- W54764250 cites W2018964056 @default.
- W54764250 cites W2019145605 @default.
- W54764250 cites W2019464448 @default.
- W54764250 cites W2019927751 @default.
- W54764250 cites W2021206826 @default.
- W54764250 cites W2022562599 @default.
- W54764250 cites W2022864922 @default.
- W54764250 cites W2024059792 @default.
- W54764250 cites W2024277408 @default.
- W54764250 cites W2026118800 @default.
- W54764250 cites W2027066860 @default.
- W54764250 cites W2028242838 @default.
- W54764250 cites W2028727099 @default.
- W54764250 cites W2029127832 @default.
- W54764250 cites W2030621225 @default.
- W54764250 cites W2032438999 @default.
- W54764250 cites W2032747448 @default.
- W54764250 cites W2034301292 @default.
- W54764250 cites W2034450065 @default.