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- W55202096 abstract "textabstractIn this thesis, the outline and the results of the fi rst part of the PeripheralNeuropathy outcome measures Standardisation (PeriNomS) study are described.The PeriNomS study aims to improve and standardise the assessment of patientswith immune-mediated neuropathies. These disorders are potentially treatablewith immuno-modulating agents, therefore, proper outcome measures are neededto detect clinically important improvement or deterioration over time.Immune-mediated neuropathies include Guillain-Barre syndrome (GBS), chronicinfl ammatory demyelinating polyneuropathy (CIDP), polyneuropathy associatedwith monoclonal gammopathy of undetermined signifi cance (MGUSP), andmultifocal motor neuropathy (MMN). Electrophysiological examination in thesepatients generally reveals features of a demyelinating polyneuropathy, although asubgroup of GBS patients may have predominantly axonal features (acute motoraxonal neuropathy (AMAN)). Diagnostic criteria for all these neuropathies havebeen formulated.1-4 From a clinical, electrophysiological, and immunologicalpoint of view there is increasing evidence that these illnesses represent part of acontinuum, mainly separated by their extent of neuromuscular dysfunction, theevolution of weakness over time, and their response to treatment (table 1). In thefollowing, a brief overview of these neuropathies is given with particular emphasison their clinical presentation." @default.
- W55202096 created "2016-06-24" @default.
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- W55202096 date "2012-01-11" @default.
- W55202096 modified "2023-09-26" @default.
- W55202096 title "Improving and standardising assessment of patients with immune-mediated neuropathies: Peripheral Neuropathy outcome measures Standardisation study (PeriNomS study – part 1)" @default.
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