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- W55277718 abstract "A vast knowledge is currently available on the molecular biology and the pharmacology of nicotinic acetylcholine receptors (nAChR) in the mammalian central nervous system (CNS) (Sargent, 1993). Only few attempts have been made to approach the expression of nAChRs at the level of functional systems, considering the different cell types involved and their connectivity. This aspect is of particular importance in order to evaluate nAChR expression under pathological conditions. Histochemical techniques have proven to be useful since immunohistochemistry and in situ hybridization can be performed on human autopsy tissue and allow for a cell type-specific localization of nAChR proteins and nAChR mRNAs. Furthermore, morphometry enables the quantitative assessment of receptor expression at the cellular level." @default.
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- W55277718 date "1994-01-01" @default.
- W55277718 modified "2023-10-06" @default.
- W55277718 title "Nicotinic Receptors in Human Brain" @default.
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- W55277718 doi "https://doi.org/10.1007/978-1-4615-8149-9_30" @default.
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