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• W55284089 abstract "Research Article1 February 1983free access The beta2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon. F. Rosa F. Rosa Institut Pasteur, Université Paris VII, France. Search for more papers by this author H. Berissi H. Berissi Institut Pasteur, Université Paris VII, France. Search for more papers by this author J. Weissenbach J. Weissenbach Institut Pasteur, Université Paris VII, France. Search for more papers by this author L. Maroteaux L. Maroteaux Institut Pasteur, Université Paris VII, France. Search for more papers by this author M. Fellous M. Fellous Institut Pasteur, Université Paris VII, France. Search for more papers by this author M. Revel M. Revel Institut Pasteur, Université Paris VII, France. Search for more papers by this author F. Rosa F. Rosa Institut Pasteur, Université Paris VII, France. Search for more papers by this author H. Berissi H. Berissi Institut Pasteur, Université Paris VII, France. Search for more papers by this author J. Weissenbach J. Weissenbach Institut Pasteur, Université Paris VII, France. Search for more papers by this author L. Maroteaux L. Maroteaux Institut Pasteur, Université Paris VII, France. Search for more papers by this author M. Fellous M. Fellous Institut Pasteur, Université Paris VII, France. Search for more papers by this author M. Revel M. Revel Institut Pasteur, Université Paris VII, France. Search for more papers by this author Author Information F. Rosa1, H. Berissi1, J. Weissenbach1, L. Maroteaux1, M. Fellous1 and M. Revel1 1Institut Pasteur, Université Paris VII, France. The EMBO Journal (1983)2:239-243https://doi.org/10.1002/j.1460-2075.1983.tb01412.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info The human Burkitt lymphoma cell line Daudi does not synthesize beta2-microglobulin (beta2m) and lacks the cell surface histocompatibility antigens. The cells, however, contain RNA hybridizing to a cloned human beta2m cDNA probe. cDNA from this Daudi beta2m RNA, was cloned and sequenced. By comparison with cDNA prepared from Ramos cells, which synthesized microglobulin, we determined the sequence of the 20 amino acid long leader peptide of pre-beta2m and show that in Daudi cells the initiator ATG has been mutated to ATC. Although Daudi beta2m RNA cannot be translated, interferon induces the beta2m RNA in Daudi cells as well as in normal human cells. Previous ArticleNext Article Volume 2Issue 21 February 1983In this issue RelatedDetailsLoading ..." @default.
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• W55284089 title "The beta2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon." @default.
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