Matches in SemOpenAlex for { <https://semopenalex.org/work/W55350511> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W55350511 endingPage "15" @default.
- W55350511 startingPage "509" @default.
- W55350511 abstract "Effects of various aminoacids and their derivatives on the classical pathway and alternative pathway of the complement were studied. Leupeptin, acetyl-leucyl-leucyl-arginal, inhibited CH50 and Cl-esterase, but did not inhibit the alternative pathway. When aminoacids of carbon chains of the order of seven were used, arginine and lysine had stronger effects than trans-aminomethyl cyclohexane carboxylic acid (t-AMCHA), cis-aminomethyl cyclohexane carboxylic acid (cis-AMCHA) and epsilon aminocaproic acid (EACA). SH-compounds, cysteine, homocysteine and glutathione, had the strongest inhibitory effects among these aminoacids on both classical and alternative pathways. When effects on Cl esterase were compared, arginine, lysine, t-AMCHA, cis-AMCHA and EACA had weak inhibition while SH-compounds showed strong inhibition. Poly-L-lysine, which had extremely strong inhibition of CH50, had no inhibition of Cl esterase. The inhibitory effects of antifibrinolytic agents, EACA and t-AMCHA, were weak but when effects on early parts of the classical pathway, C(1,4,2)H50 were tested, some inhibitory activities were recognized. Thus inhibitory effects of these agents were due to their activities on the early parts of the classical pathway." @default.
- W55350511 created "2016-06-24" @default.
- W55350511 creator A5000834556 @default.
- W55350511 creator A5019158744 @default.
- W55350511 creator A5022174313 @default.
- W55350511 creator A5062872296 @default.
- W55350511 date "1978-03-01" @default.
- W55350511 modified "2023-10-18" @default.
- W55350511 title "Inhibition of the classical and alternative pathways by amino acids and their derivatives." @default.
- W55350511 cites W1482593346 @default.
- W55350511 cites W1517076645 @default.
- W55350511 cites W1548143595 @default.
- W55350511 cites W1575418040 @default.
- W55350511 cites W1608351824 @default.
- W55350511 cites W1608773321 @default.
- W55350511 cites W1780883998 @default.
- W55350511 cites W1996820575 @default.
- W55350511 cites W2006623568 @default.
- W55350511 cites W2070875737 @default.
- W55350511 cites W2085196275 @default.
- W55350511 cites W2098549028 @default.
- W55350511 cites W2131233813 @default.
- W55350511 cites W2418670398 @default.
- W55350511 cites W2466787110 @default.
- W55350511 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1457603" @default.
- W55350511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/305891" @default.
- W55350511 hasPublicationYear "1978" @default.
- W55350511 type Work @default.
- W55350511 sameAs 55350511 @default.
- W55350511 citedByCount "21" @default.
- W55350511 crossrefType "journal-article" @default.
- W55350511 hasAuthorship W55350511A5000834556 @default.
- W55350511 hasAuthorship W55350511A5019158744 @default.
- W55350511 hasAuthorship W55350511A5022174313 @default.
- W55350511 hasAuthorship W55350511A5062872296 @default.
- W55350511 hasConcept C169760540 @default.
- W55350511 hasConcept C17077164 @default.
- W55350511 hasConcept C181199279 @default.
- W55350511 hasConcept C185592680 @default.
- W55350511 hasConcept C2776016237 @default.
- W55350511 hasConcept C2777261171 @default.
- W55350511 hasConcept C2777468819 @default.
- W55350511 hasConcept C2779201268 @default.
- W55350511 hasConcept C2779303437 @default.
- W55350511 hasConcept C515207424 @default.
- W55350511 hasConcept C55493867 @default.
- W55350511 hasConcept C71240020 @default.
- W55350511 hasConcept C86803240 @default.
- W55350511 hasConceptScore W55350511C169760540 @default.
- W55350511 hasConceptScore W55350511C17077164 @default.
- W55350511 hasConceptScore W55350511C181199279 @default.
- W55350511 hasConceptScore W55350511C185592680 @default.
- W55350511 hasConceptScore W55350511C2776016237 @default.
- W55350511 hasConceptScore W55350511C2777261171 @default.
- W55350511 hasConceptScore W55350511C2777468819 @default.
- W55350511 hasConceptScore W55350511C2779201268 @default.
- W55350511 hasConceptScore W55350511C2779303437 @default.
- W55350511 hasConceptScore W55350511C515207424 @default.
- W55350511 hasConceptScore W55350511C55493867 @default.
- W55350511 hasConceptScore W55350511C71240020 @default.
- W55350511 hasConceptScore W55350511C86803240 @default.
- W55350511 hasIssue "3" @default.
- W55350511 hasLocation W553505111 @default.
- W55350511 hasOpenAccess W55350511 @default.
- W55350511 hasPrimaryLocation W553505111 @default.
- W55350511 hasRelatedWork W1225836934 @default.
- W55350511 hasRelatedWork W1682642099 @default.
- W55350511 hasRelatedWork W188155302 @default.
- W55350511 hasRelatedWork W2013691430 @default.
- W55350511 hasRelatedWork W2024963885 @default.
- W55350511 hasRelatedWork W2033907782 @default.
- W55350511 hasRelatedWork W2052099900 @default.
- W55350511 hasRelatedWork W2081940762 @default.
- W55350511 hasRelatedWork W2127389729 @default.
- W55350511 hasRelatedWork W3022776727 @default.
- W55350511 hasVolume "34" @default.
- W55350511 isParatext "false" @default.
- W55350511 isRetracted "false" @default.
- W55350511 magId "55350511" @default.
- W55350511 workType "article" @default.