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• W55442648 startingPage "722" @default.
• W55442648 abstract "Abstract Immunophenotyping studies with monoclonal antibodies have revealed the heterogeneity of childhood acute lymphoblastic leukemia (ALL) and non- Hodgkin's lymphoma (NHL). The lymphoid malignancies of T-cell lineage are particularly heterogeneous and, until now, no single monoclonal antibody has been found to identify all cases of T-ALL and T-NHL. A monoclonal antibody, 4H9, recognizes an antigen of 40,000 molecular weight on normal and malignant T cells. Thirty-six cases of childhood T- ALL and T-NHL were tested, and in all cases, the malignant blast cells were reactive with 4H9, whereas malignant cells from 61 cases of non-T ALL and NHL were not reactive with 4H9. Monoclonal antibody 4H9 is a sensitive and specific reagent for the identification of childhood T- cell ALL and NHL and should be extremely useful in immunophenotyping studies of lymphoid malignancies." @default.
• W55442648 created "2016-06-24" @default.
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• W55442648 date "1983-10-01" @default.
• W55442648 modified "2023-09-27" @default.
• W55442648 title "A single monoclonal antibody identifies T-cell lineage of childhood lymphoid malignancies" @default.
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• W55442648 doi "https://doi.org/10.1182/blood.v62.4.722.722" @default.
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