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- W5592899 abstract "788 Learning Objectives: The objectives of this educational exhibit are to 1. describe the prevalence and significance of thyroglobulin positive (TG+) and radioiodine (RAI) negative diagnostic (dx) whole body scans (WBS-) in patients with well-differentiated thyroid cancer (WDTC). 2. Identify possible causes of falsely elevated serum TG levels and falsely negative Dx WBSs in TG+/WBS- patients, 3. Discuss the arguments for and against RAI treatment of TG+/Dx WBS- patients (blind treatment), and 4. Discuss the arguments for and against further evaluation with other imaging modalities and, when appropriate, intervention with other therapies. Abstract Body: TG and RAI WBSs are utilized in follow up of patients with WDTC as indicators of residual or recurrent WDTC. Management of patients who are TG+ and RAI WBS- is controversial. Management options include (1) blind (meaning no evidence of functioning metastases on WBS) treatment with RAI, (2) further evaluation with other imaging modalities to try to identify the source of the elevated TG with possible subsequent diagnostic management such as FNA and/or various therapeutic interventions, and (3) monitoring the patient for evidence of disease progression (e.g. increasing TG levels). However, large prospective studies regarding outcomes of any of these approaches are not available, and each has arguments for and against its use. This educational exhibit will review the literature regarding those arguments, and this information will be useful to the practitioners managing these patients." @default.
- W5592899 created "2016-06-24" @default.
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- W5592899 date "2008-05-01" @default.
- W5592899 modified "2023-09-25" @default.
- W5592899 title "To treat or not to treat thyroglobulin-positive and radioiodine diagnostic whole body scan negative patients with well-differentiated thyroid cancer: An educational exhibit" @default.
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