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- W560701317 abstract "Biotransformation and detoxification responses to the exposure to five polycyclic aromatic hydrocarbons were investigated in crucian(Carassius auratus). Juvenile crucian were treated with a single intraperitoneal injection of each compound at dosages of 0.1, 1.0, 2.0, 5.0 and 8.0(or 10.0) mg/kg and sacrificed 15 d later to determine 7-ethoxyresorufin-O-deethylase(EROD) and glutathione S-transferases(GST) activities in gill S9 fractions. EROD activity is significantly increased by benzo(b)fluoranthene and indeno(1,2,3-cd)pyrene at all the doses. High dosages of PAHs induced GST activity and the inducing ability of them increased in the following order: fluorene< fluoranthene<indeno(1,2,3-cd)pyrene<benzo(g,h,i)perylene<benzo(b)fluoranthene. In all the cases, dose dependence appeared to exist. The gill EROD and GST in Carassius auratus are useful biomarkers to estimate sub-acute toxicity of both polycyclic aromatic hydrocarbons(PAHs) and PAHs-like compounds. Keywords Polycyclic aromatic hydrocarbon; Gill; 7-Ethoxyresorufin-O-deethylase activity; Glutathione S-transfe- rases activity Article ID 1005-9040(2011)-03-413-04" @default.
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- W560701317 date "2011-01-01" @default.
- W560701317 modified "2023-09-24" @default.
- W560701317 title "Effects of PAHs on Biotransformation Enzymatic Activities in Fish" @default.
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