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- W562204940 abstract "Segmental neurofibromatosis type 1 (NF1) describes patients with manifestations of NF1 that are restricted to one region of the body; little has been documented in the way of significant medical or developmental problems in patients with segmental NF1 that are frequently noted in generalized NF1. We performed a retrospective review of patients with segmental NF1 to determine the prevalence of academic and cognitive difficulties in children with segmental NF1 compared to children with generalized NF1. A total of 62 patients were identified with segmental NF1. Almost all patients had pigmentary changes with cafeau lait macules and skin-fold freckling that were limited to one region of the body. Nearly half of children with segmental NF1 had individualized educational plans and received supportive academic services (47%, which was close to the frequency of 57% in generalized NF1). This study provides preliminary evidence that children with segmental NF1 may be at increased risk for academic and cognitive difficulties. We recommend close follow-up and developmental screening of all children with segmental NF1, as is done for children with generalized NF1." @default.
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- W562204940 date "2015-07-30" @default.
- W562204940 modified "2023-09-23" @default.
- W562204940 title "Children with segmental neurofibromatosis type 1 are at increased risk for academic and cognitive difficulties" @default.
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- W562204940 doi "https://doi.org/10.3233/jpn-2010-0411" @default.
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