Matches in SemOpenAlex for { <https://semopenalex.org/work/W562260026> ?p ?o ?g. }
- W562260026 endingPage "194" @default.
- W562260026 startingPage "186" @default.
- W562260026 abstract "The role of nitric oxide (NO) in host defense against Echinococcus granulosus larvae was previously reported. However, NO production by NOS2 (inducible NO synthase) is counteracted by the expression of Arginase. In the present study, our aim is to evaluate the involvement of the laminated layer (external layer of parasitic cyst) in Arginase induction and the protoscoleces (living and infective part of the cyst) survival. Our in vitro results indicate that this cystic compound increases the Arginase activity in macrophages. Moreover, C-type lectin receptors (CLRs) with specificity for mannan and the TGF-β are implicated in this effect as shown after adding Mannan and Anti-TGFβ. Interestingly, the laminated layer increases protoscoleces survival in macrophages-parasite co-cultures. Our results indicate that the laminated layer protects E. granulosus against the NOS2 protective response through Arginase pathway, a hallmark of M2 macrophages." @default.
- W562260026 created "2016-06-24" @default.
- W562260026 creator A5042109271 @default.
- W562260026 creator A5057901336 @default.
- W562260026 date "2015-09-01" @default.
- W562260026 modified "2023-09-25" @default.
- W562260026 title "A protective effect of the laminated layer on Echinococcus granulosus survival dependent on upregulation of host arginase" @default.
- W562260026 cites W1490103513 @default.
- W562260026 cites W1576587813 @default.
- W562260026 cites W1645729271 @default.
- W562260026 cites W1962869168 @default.
- W562260026 cites W1968730380 @default.
- W562260026 cites W1969610841 @default.
- W562260026 cites W1978442399 @default.
- W562260026 cites W1980847116 @default.
- W562260026 cites W1988128973 @default.
- W562260026 cites W1989440320 @default.
- W562260026 cites W2003738054 @default.
- W562260026 cites W2015192504 @default.
- W562260026 cites W2027065592 @default.
- W562260026 cites W2028631237 @default.
- W562260026 cites W2033204353 @default.
- W562260026 cites W2038461328 @default.
- W562260026 cites W2045796965 @default.
- W562260026 cites W2046652062 @default.
- W562260026 cites W2052472146 @default.
- W562260026 cites W2055214445 @default.
- W562260026 cites W2055290849 @default.
- W562260026 cites W2062200101 @default.
- W562260026 cites W2070616542 @default.
- W562260026 cites W2072243674 @default.
- W562260026 cites W2079276179 @default.
- W562260026 cites W2089937844 @default.
- W562260026 cites W2090788653 @default.
- W562260026 cites W2090862497 @default.
- W562260026 cites W2091080027 @default.
- W562260026 cites W2091413967 @default.
- W562260026 cites W2092169332 @default.
- W562260026 cites W2092288580 @default.
- W562260026 cites W2094138369 @default.
- W562260026 cites W2100965799 @default.
- W562260026 cites W2102520038 @default.
- W562260026 cites W2104032278 @default.
- W562260026 cites W2106432468 @default.
- W562260026 cites W2115545988 @default.
- W562260026 cites W2116731331 @default.
- W562260026 cites W2123117008 @default.
- W562260026 cites W2127509295 @default.
- W562260026 cites W2127984506 @default.
- W562260026 cites W2136415390 @default.
- W562260026 cites W2142725506 @default.
- W562260026 cites W2143043043 @default.
- W562260026 cites W2146136167 @default.
- W562260026 cites W2146213573 @default.
- W562260026 cites W2156908197 @default.
- W562260026 cites W4293247451 @default.
- W562260026 doi "https://doi.org/10.1016/j.actatropica.2015.05.027" @default.
- W562260026 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26048557" @default.
- W562260026 hasPublicationYear "2015" @default.
- W562260026 type Work @default.
- W562260026 sameAs 562260026 @default.
- W562260026 citedByCount "25" @default.
- W562260026 countsByYear W5622600262016 @default.
- W562260026 countsByYear W5622600262017 @default.
- W562260026 countsByYear W5622600262018 @default.
- W562260026 countsByYear W5622600262019 @default.
- W562260026 countsByYear W5622600262020 @default.
- W562260026 countsByYear W5622600262021 @default.
- W562260026 countsByYear W5622600262022 @default.
- W562260026 countsByYear W5622600262023 @default.
- W562260026 crossrefType "journal-article" @default.
- W562260026 hasAuthorship W562260026A5042109271 @default.
- W562260026 hasAuthorship W562260026A5057901336 @default.
- W562260026 hasConcept C100817775 @default.
- W562260026 hasConcept C104317684 @default.
- W562260026 hasConcept C127561419 @default.
- W562260026 hasConcept C134018914 @default.
- W562260026 hasConcept C136764020 @default.
- W562260026 hasConcept C164007495 @default.
- W562260026 hasConcept C165901193 @default.
- W562260026 hasConcept C202751555 @default.
- W562260026 hasConcept C203014093 @default.
- W562260026 hasConcept C2775963980 @default.
- W562260026 hasConcept C2777028278 @default.
- W562260026 hasConcept C2777468819 @default.
- W562260026 hasConcept C2779452502 @default.
- W562260026 hasConcept C2779719659 @default.
- W562260026 hasConcept C41008148 @default.
- W562260026 hasConcept C515207424 @default.
- W562260026 hasConcept C519581460 @default.
- W562260026 hasConcept C55493867 @default.
- W562260026 hasConcept C71928629 @default.
- W562260026 hasConcept C86803240 @default.
- W562260026 hasConcept C89423630 @default.
- W562260026 hasConcept C90856448 @default.
- W562260026 hasConceptScore W562260026C100817775 @default.
- W562260026 hasConceptScore W562260026C104317684 @default.
- W562260026 hasConceptScore W562260026C127561419 @default.