Matches in SemOpenAlex for { <https://semopenalex.org/work/W562364274> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W562364274 endingPage "82" @default.
- W562364274 startingPage "75" @default.
- W562364274 abstract "Five peptide renin inhibitors containing the sequence: Phe-His-Sta-epsilon Ahx (Sta = 4(S)-amino-3(S)-hydroxy-6-methylheptanoic acid, epsilon Ahx = 6-aminohexanoic acid) were synthesized and their potency was assayed in vitro by a spectrofluorometric method (assay of Leu-Val-Tyr-Ser released from N-acetyltetradecapeptide substrate by renin in the presence of an inhibitor). Their stability was tested by assay of Phe and Pro-Phe released after incubation with chymotrypsin. The most potent inhibitor was Boc-Phe-His-Sta-epsilon Ahx-OMe (IC50 = 5 x 10(-9) M/l), the most stable--Boc-Pro-Phe-His-Sta-epsilon Ahx-OMe (resistant to incubation with chymotrypsin for 4 h)." @default.
- W562364274 created "2016-06-24" @default.
- W562364274 creator A5029132679 @default.
- W562364274 creator A5058479920 @default.
- W562364274 creator A5068077684 @default.
- W562364274 date "1993-01-01" @default.
- W562364274 modified "2023-09-23" @default.
- W562364274 title "Renin inhibitors containing statine and 6-aminohexanoic acid. Part III." @default.
- W562364274 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8401762" @default.
- W562364274 hasPublicationYear "1993" @default.
- W562364274 type Work @default.
- W562364274 sameAs 562364274 @default.
- W562364274 citedByCount "1" @default.
- W562364274 crossrefType "journal-article" @default.
- W562364274 hasAuthorship W562364274A5029132679 @default.
- W562364274 hasAuthorship W562364274A5058479920 @default.
- W562364274 hasAuthorship W562364274A5068077684 @default.
- W562364274 hasConcept C134018914 @default.
- W562364274 hasConcept C181199279 @default.
- W562364274 hasConcept C185592680 @default.
- W562364274 hasConcept C198710026 @default.
- W562364274 hasConcept C202751555 @default.
- W562364274 hasConcept C25642318 @default.
- W562364274 hasConcept C2776980637 @default.
- W562364274 hasConcept C2777425892 @default.
- W562364274 hasConcept C2777752497 @default.
- W562364274 hasConcept C2778401398 @default.
- W562364274 hasConcept C2779281246 @default.
- W562364274 hasConcept C2780340462 @default.
- W562364274 hasConcept C55493867 @default.
- W562364274 hasConcept C57992300 @default.
- W562364274 hasConcept C71240020 @default.
- W562364274 hasConcept C84393581 @default.
- W562364274 hasConcept C86803240 @default.
- W562364274 hasConceptScore W562364274C134018914 @default.
- W562364274 hasConceptScore W562364274C181199279 @default.
- W562364274 hasConceptScore W562364274C185592680 @default.
- W562364274 hasConceptScore W562364274C198710026 @default.
- W562364274 hasConceptScore W562364274C202751555 @default.
- W562364274 hasConceptScore W562364274C25642318 @default.
- W562364274 hasConceptScore W562364274C2776980637 @default.
- W562364274 hasConceptScore W562364274C2777425892 @default.
- W562364274 hasConceptScore W562364274C2777752497 @default.
- W562364274 hasConceptScore W562364274C2778401398 @default.
- W562364274 hasConceptScore W562364274C2779281246 @default.
- W562364274 hasConceptScore W562364274C2780340462 @default.
- W562364274 hasConceptScore W562364274C55493867 @default.
- W562364274 hasConceptScore W562364274C57992300 @default.
- W562364274 hasConceptScore W562364274C71240020 @default.
- W562364274 hasConceptScore W562364274C84393581 @default.
- W562364274 hasConceptScore W562364274C86803240 @default.
- W562364274 hasIssue "1" @default.
- W562364274 hasLocation W5623642741 @default.
- W562364274 hasOpenAccess W562364274 @default.
- W562364274 hasPrimaryLocation W5623642741 @default.
- W562364274 hasRelatedWork W1969592663 @default.
- W562364274 hasRelatedWork W1975998295 @default.
- W562364274 hasRelatedWork W2020700034 @default.
- W562364274 hasRelatedWork W2041617273 @default.
- W562364274 hasRelatedWork W2052188727 @default.
- W562364274 hasRelatedWork W2053429551 @default.
- W562364274 hasRelatedWork W2072253789 @default.
- W562364274 hasRelatedWork W2086593457 @default.
- W562364274 hasRelatedWork W2394847973 @default.
- W562364274 hasRelatedWork W562364274 @default.
- W562364274 hasVolume "45" @default.
- W562364274 isParatext "false" @default.
- W562364274 isRetracted "false" @default.
- W562364274 magId "562364274" @default.
- W562364274 workType "article" @default.