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- W56268191 abstract "Eleven analogues of L-arginyl-D-allo-threonyl-L-phenylalanine, a naturally occurring peptide with antifungal activity, were synthesized. Two tripeptides of the form L-arginyl-X-L-phenylalanine (X = p-F-DL-phenylalanine or m-F-DL-tyrosine) inhibited Aspergillus fumigatus and Aspergillus flavus. In comparison with the free antagonists, the tripeptide-bound antagonists were more active against Candida-albicans-isolates which means that the amino acid sequence may serve as carrier function: it enhances delivery or uptake of the antimetabolite." @default.
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- W56268191 date "1982-01-01" @default.
- W56268191 modified "2023-09-25" @default.
- W56268191 title "The Antifungal Activity of Carrier Peptides, L-arginyl-X-L-phenylalanine, Containing Amino Acid Antagonists or Atypical Non-Biogenic D-Amino Acids in the Central Position" @default.
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- W56268191 doi "https://doi.org/10.1016/s0174-3031(82)80126-1" @default.
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