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• W563945376 abstract "Introduction and Aims: The progressive nature of heart failure (HF) is reflected by its complex pathophysiology, featured by imbalance of damaging and reparative factors. The overall aim was to assess the implication of endothelial (dys)function, monocyte subsets, different types of endothelial progenitors and plasma microparticles in subjects with HF. A special focus was an investigation of possible ethnic differences in these parameters. Methods: Parameters of vascular function, monocyte subsets, endothelial progenitors, and cellular microparticles were compared between South Asian subjects with systolic HF, and those with heart disease without HF and healthy controls. Ethnic differences in HF were assessed in three ethnic groups: South Asians, Whites, and African-Caribbeans. Additionally, leukocyte counts were compared between subjects with HF with reduced or preserved ejection fraction, whose outcome (mortality) was recorded during follow-up. Results: South Asian subjects with HF had significantly impaired micro- and macrovascular endothelial function, reduced levels of endothelial progenitors, and monocytes with reparative potential, but increased levels of microparticles. In HF patients, a high count of monocyte microparticles was associated with low ejection fraction. There were significant ethnic differences in characteristics of microvascular endothelial function, counts of CD14++CD16+ and CD14+CD16++ monocytes and monocyte-derived endothelial progenitors. On multivariate analysis, a high monocyte count was a significant predictor of death in HF with preserved ejection fraction unlike in those with systolic HF. Conclusions: Significant impairment of microvascular endothelial function is present in South Asian subjects with HF. High monocyte count is an independent predictor of death in HF with preserved ejection fraction. The value of the tested biological markers as therapeutic targets should be explored in future studies." @default.
• W563945376 created "2016-06-24" @default.
• W563945376 creator A5065851369 @default.
• W563945376 date "2012-07-01" @default.
• W563945376 modified "2023-09-26" @default.
• W563945376 title "Ethnic differences in endothelial function and monocyte subsets in heart failure" @default.
• W563945376 cites W111332543 @default.
• W563945376 cites W1228803923 @default.
• W563945376 cites W134119418 @default.
• W563945376 cites W140667287 @default.
• W563945376 cites W1410931458 @default.
• W563945376 cites W146136786 @default.
• W563945376 cites W1489988243 @default.
• W563945376 cites W1495287184 @default.
• W563945376 cites W1496810310 @default.
• W563945376 cites W1508082942 @default.
• W563945376 cites W1513548367 @default.
• W563945376 cites W1521100056 @default.
• W563945376 cites W1535567348 @default.
• W563945376 cites W1541901307 @default.
• W563945376 cites W1551555680 @default.
• W563945376 cites W155381766 @default.
• W563945376 cites W1555489744 @default.
• W563945376 cites W1563390562 @default.
• W563945376 cites W1566419077 @default.
• W563945376 cites W1570471712 @default.
• W563945376 cites W1575990528 @default.
• W563945376 cites W1578606146 @default.
• W563945376 cites W1580145878 @default.
• W563945376 cites W1599975943 @default.
• W563945376 cites W1664379753 @default.
• W563945376 cites W182898904 @default.
• W563945376 cites W1893775 @default.
• W563945376 cites W1916529790 @default.
• W563945376 cites W1955246945 @default.
• W563945376 cites W1963757968 @default.
• W563945376 cites W1964367738 @default.
• W563945376 cites W1964424494 @default.
• W563945376 cites W1964712648 @default.
• W563945376 cites W1964714332 @default.
• W563945376 cites W1964835513 @default.
• W563945376 cites W1965184121 @default.
• W563945376 cites W1965459344 @default.
• W563945376 cites W1965524611 @default.
• W563945376 cites W1965859404 @default.
• W563945376 cites W1966219872 @default.
• W563945376 cites W1967371148 @default.
• W563945376 cites W1967785796 @default.
• W563945376 cites W1967970013 @default.
• W563945376 cites W1968356216 @default.
• W563945376 cites W1968861411 @default.
• W563945376 cites W1969080919 @default.
• W563945376 cites W1969235931 @default.
• W563945376 cites W1969889097 @default.
• W563945376 cites W1970017301 @default.
• W563945376 cites W1970077459 @default.
• W563945376 cites W1970097197 @default.
• W563945376 cites W1970134769 @default.
• W563945376 cites W1970752167 @default.
• W563945376 cites W1971167098 @default.
• W563945376 cites W1972275957 @default.
• W563945376 cites W1972703187 @default.
• W563945376 cites W1972706982 @default.
• W563945376 cites W1973022622 @default.
• W563945376 cites W1974769258 @default.
• W563945376 cites W1975027753 @default.
• W563945376 cites W1975054771 @default.
• W563945376 cites W1975066490 @default.
• W563945376 cites W1976460214 @default.
• W563945376 cites W1977158361 @default.
• W563945376 cites W1977605936 @default.
• W563945376 cites W1978294289 @default.
• W563945376 cites W1978536893 @default.
• W563945376 cites W1978859651 @default.
• W563945376 cites W1979828226 @default.
• W563945376 cites W1980000060 @default.
• W563945376 cites W1980468558 @default.
• W563945376 cites W1980577921 @default.
• W563945376 cites W1980699020 @default.
• W563945376 cites W1981065823 @default.
• W563945376 cites W1981115336 @default.
• W563945376 cites W1982037445 @default.
• W563945376 cites W1982345842 @default.
• W563945376 cites W1982380739 @default.
• W563945376 cites W1982416548 @default.
• W563945376 cites W1982533403 @default.
• W563945376 cites W1982642213 @default.
• W563945376 cites W1982657650 @default.
• W563945376 cites W1982977879 @default.
• W563945376 cites W1983102904 @default.
• W563945376 cites W1983964548 @default.
• W563945376 cites W1984235771 @default.
• W563945376 cites W1984378291 @default.
• W563945376 cites W1984430950 @default.
• W563945376 cites W1984508574 @default.
• W563945376 cites W1984514918 @default.
• W563945376 cites W1985265801 @default.
• W563945376 cites W1985349972 @default.
• W563945376 cites W1985502949 @default.
• W563945376 cites W1986125844 @default.

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