Matches in SemOpenAlex for { <https://semopenalex.org/work/W564854792> ?p ?o ?g. }
- W564854792 abstract "Biochemical reactions of phosphate and sulfate esters are ubiquitous in the living world, and are found throughout many pathways involving metabolism, biosynthesis, control of transcription, energy storage, and replication. This chapter describes the mechanisms by which phosphate and sulfate monoesters undergo uncatalyzed and enzyme-catalyzed hydrolysis by phosphatases and sulfatases, respectively. Relative to the slow rates of the uncatalyzed reactions of their substrates, these enzymes produce rate accelerations that are among the greatest of any enzymes yet described. Interestingly, nature has evolved several quite different catalytic strategies to accomplish this. This review summarizes the current state of knowledge of several phosphatases and sulfatases. Phosphatases and sulfatases constitute a large group of enzymes, with structural and mechanistic diverseness. Within each group, one finds enzymes that utilize completely different catalytic machinery and mechanisms to accomplish the same reaction. We also summarize the mechanistic tools that have been used to study the chemistry and biochemistry of sulfate and phosphate esters, with references to comprehensive treatments of these methods for those who wish more thorough explanations of the tools of enzymology and physical organic chemistry." @default.
- W564854792 created "2016-06-24" @default.
- W564854792 creator A5000083325 @default.
- W564854792 creator A5085595230 @default.
- W564854792 date "2016-01-01" @default.
- W564854792 modified "2023-10-14" @default.
- W564854792 title "Phosphoryl and Sulfuryl Transfer☆" @default.
- W564854792 cites W1003489756 @default.
- W564854792 cites W1022007380 @default.
- W564854792 cites W116774536 @default.
- W564854792 cites W1423885963 @default.
- W564854792 cites W148204302 @default.
- W564854792 cites W1492237429 @default.
- W564854792 cites W1516913118 @default.
- W564854792 cites W1525924964 @default.
- W564854792 cites W1538925875 @default.
- W564854792 cites W1539699466 @default.
- W564854792 cites W1553375567 @default.
- W564854792 cites W1558415469 @default.
- W564854792 cites W1568472295 @default.
- W564854792 cites W1568494138 @default.
- W564854792 cites W1573991684 @default.
- W564854792 cites W1580813094 @default.
- W564854792 cites W1592392458 @default.
- W564854792 cites W1595102998 @default.
- W564854792 cites W1595702560 @default.
- W564854792 cites W1596210571 @default.
- W564854792 cites W1599175061 @default.
- W564854792 cites W1600588308 @default.
- W564854792 cites W1604205771 @default.
- W564854792 cites W1607286065 @default.
- W564854792 cites W1608368262 @default.
- W564854792 cites W175533280 @default.
- W564854792 cites W1833680771 @default.
- W564854792 cites W1933079471 @default.
- W564854792 cites W1954690293 @default.
- W564854792 cites W1965695983 @default.
- W564854792 cites W1966445705 @default.
- W564854792 cites W1966916880 @default.
- W564854792 cites W1967018847 @default.
- W564854792 cites W1967506071 @default.
- W564854792 cites W1969015290 @default.
- W564854792 cites W1969173610 @default.
- W564854792 cites W1970279804 @default.
- W564854792 cites W1970444299 @default.
- W564854792 cites W1970961719 @default.
- W564854792 cites W1971307169 @default.
- W564854792 cites W1971421895 @default.
- W564854792 cites W1971669331 @default.
- W564854792 cites W1973275503 @default.
- W564854792 cites W1973468868 @default.
- W564854792 cites W1974614256 @default.
- W564854792 cites W1975107946 @default.
- W564854792 cites W1976454923 @default.
- W564854792 cites W1976883608 @default.
- W564854792 cites W1977242499 @default.
- W564854792 cites W1978840198 @default.
- W564854792 cites W1979285357 @default.
- W564854792 cites W1979389772 @default.
- W564854792 cites W1979532713 @default.
- W564854792 cites W1980363424 @default.
- W564854792 cites W1980505823 @default.
- W564854792 cites W1980760311 @default.
- W564854792 cites W1981061846 @default.
- W564854792 cites W1981320736 @default.
- W564854792 cites W1982007696 @default.
- W564854792 cites W1982144407 @default.
- W564854792 cites W1984296057 @default.
- W564854792 cites W1985008832 @default.
- W564854792 cites W1985023196 @default.
- W564854792 cites W1985684677 @default.
- W564854792 cites W1985770761 @default.
- W564854792 cites W1987068920 @default.
- W564854792 cites W1987867414 @default.
- W564854792 cites W1988927521 @default.
- W564854792 cites W1989276141 @default.
- W564854792 cites W1989554073 @default.
- W564854792 cites W1990417626 @default.
- W564854792 cites W1992532108 @default.
- W564854792 cites W1993620005 @default.
- W564854792 cites W1994103683 @default.
- W564854792 cites W1994157033 @default.
- W564854792 cites W1994475293 @default.
- W564854792 cites W1995425581 @default.
- W564854792 cites W1995557109 @default.
- W564854792 cites W1995690959 @default.
- W564854792 cites W1996101432 @default.
- W564854792 cites W1998859207 @default.
- W564854792 cites W1999795382 @default.
- W564854792 cites W2000051116 @default.
- W564854792 cites W2000394780 @default.
- W564854792 cites W2000497765 @default.
- W564854792 cites W2001521415 @default.
- W564854792 cites W2002979052 @default.
- W564854792 cites W2003836093 @default.
- W564854792 cites W2006128611 @default.
- W564854792 cites W2007551386 @default.
- W564854792 cites W2007796873 @default.
- W564854792 cites W2008185082 @default.
- W564854792 cites W2008188668 @default.