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- W56517949 abstract "Voltage-gated sodium (Na) channels are transmembrane proteins responsible for the rapid upstroke of the cardiac action potential, and therefore underlie impulse conduction through much of the myocardium. Thus, Na channels are key molecular substrates in both inherited and acquired disorders of cardiac excitability. Ongoing efforts to reconcile emerging Na channel structural data with assays revealing insights into biophysic function are forming a framework to develop more precise interventions to modify cardiac excitability and to treat disorders of cardiac rhythm." @default.
- W56517949 created "2016-06-24" @default.
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- W56517949 date "2004-01-01" @default.
- W56517949 modified "2023-09-26" @default.
- W56517949 title "Biophysics of Normal and Abnormal Cardiac Sodium Channel Function" @default.
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- W56517949 doi "https://doi.org/10.1016/b0-7216-0323-8/50012-9" @default.
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