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- W565546861 abstract "The use of transition metal complexes as tools for molecular biology is reviewed. Two basic strategies are detailed: the design and synthesis of metal complexes that recognize, bind to, and cleave DNA, and the use of a metal complex [iron(II) EDTA] that cleaves DNA non-specifically through generation of free hydroxyl radical. Application of the latter strategy to the determination of the helical periodicity of viral promoter DNA, and structural details of bent DNA from a trypanosomatid parasite, are presented." @default.
- W565546861 created "2016-06-24" @default.
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- W565546861 date "1989-08-10" @default.
- W565546861 modified "2023-09-23" @default.
- W565546861 title "Metal-DNA Chemistry" @default.
- W565546861 doi "https://doi.org/10.1021/bk-1989-0402" @default.
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