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- W56637210 abstract "Abstract Cysteine inhibits growth of Escherichia coli by blocking isoleucine synthesis, presumably at the level of threonine deaminase (Harris, C.L. 1981. J. Bacteriol. 145 , 1031–1035). We show here that treatment of growing cultures with cysteine causes a decrease in the % charging of tRNAile, in proportion to the extent of growth inhibition. This effect is accompanied by a partial derepression of the ilvGEDA operon. These findings suggest a new way to limit isoleucine synthesis in E. coli which may be useful for studies of regulation of the ilvGEDA operon." @default.
- W56637210 created "2016-06-24" @default.
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- W56637210 date "1981-08-01" @default.
- W56637210 modified "2023-10-01" @default.
- W56637210 title "Cysteine and growth inhibition of Escherichiacoli: Derepression of the ilvGEDA operon" @default.
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- W56637210 doi "https://doi.org/10.1016/0006-291x(81)91567-9" @default.
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