Matches in SemOpenAlex for { <https://semopenalex.org/work/W566853810> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W566853810 abstract "We have already confirmed that symptoms in the experimental UC model in rats induced by ingesting DSS resembled those of human UC. In the present study, to clarify the participation of chemical mediators concerned with the development and etiology of the experimental UC model, we investigated the effects of superoxide dismutase (SOD), 5-aminosalicylic acid (5-ASA), AA-861, an LTB4-receptor antagonist (LTB4-ra), indomethacin (Ind) and OKY-046 on the DSS-induced UC model in rats. The UC model was produced by giving rats drinking water containing 3% DSS, and animals were selected when bloody stool was observed in more than 90% of the animals. After selection, drugs were intrarectally administered once a day, for 7 days, to UC rats that were given drinking water containing 1% DSS. SOD, 5-ASA, AA-861 and LTB4-ra inhibited the formation of erosions in the large intestine. Furthermore, SOD, 5-ASA and LTB4-ra improved the length of the large intestine of rats that had been shortened by ingesting DSS. On the other hand, neither Ind nor OKY-046 improved the shortening and erosion of the large intestine. From these results, it is concluded that the free radical and lipoxygenase metabolites of arachidonic acid may be partially involved in the DSS-induced UC model in rats." @default.
- W566853810 created "2016-06-24" @default.
- W566853810 creator A5001153919 @default.
- W566853810 creator A5025692781 @default.
- W566853810 creator A5046899439 @default.
- W566853810 creator A5062385806 @default.
- W566853810 creator A5082350803 @default.
- W566853810 date "1996-01-01" @default.
- W566853810 modified "2023-09-25" @default.
- W566853810 title "Study on the experimental ulcerative colitis(UC) model induced by dextran sulfate sodium(DSS) in rats. (3)." @default.
- W566853810 cites W1662486898 @default.
- W566853810 cites W1973173167 @default.
- W566853810 cites W2008574207 @default.
- W566853810 cites W2022445623 @default.
- W566853810 cites W2050941520 @default.
- W566853810 cites W2059557859 @default.
- W566853810 cites W2076460434 @default.
- W566853810 cites W2079773688 @default.
- W566853810 cites W2094791820 @default.
- W566853810 cites W2130387436 @default.
- W566853810 cites W2166525518 @default.
- W566853810 cites W2168979139 @default.
- W566853810 cites W2315700988 @default.
- W566853810 cites W2322570099 @default.
- W566853810 cites W2426972604 @default.
- W566853810 cites W2460497393 @default.
- W566853810 cites W2467752149 @default.
- W566853810 cites W315764148 @default.
- W566853810 doi "https://doi.org/10.1254/fpj.108.259" @default.
- W566853810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8974086" @default.
- W566853810 hasPublicationYear "1996" @default.
- W566853810 type Work @default.
- W566853810 sameAs 566853810 @default.
- W566853810 citedByCount "9" @default.
- W566853810 countsByYear W5668538102014 @default.
- W566853810 countsByYear W5668538102018 @default.
- W566853810 crossrefType "journal-article" @default.
- W566853810 hasAuthorship W566853810A5001153919 @default.
- W566853810 hasAuthorship W566853810A5025692781 @default.
- W566853810 hasAuthorship W566853810A5046899439 @default.
- W566853810 hasAuthorship W566853810A5062385806 @default.
- W566853810 hasAuthorship W566853810A5082350803 @default.
- W566853810 hasBestOaLocation W5668538101 @default.
- W566853810 hasConcept C126322002 @default.
- W566853810 hasConcept C179998833 @default.
- W566853810 hasConcept C181199279 @default.
- W566853810 hasConcept C185592680 @default.
- W566853810 hasConcept C2775838275 @default.
- W566853810 hasConcept C2775862500 @default.
- W566853810 hasConcept C2776918747 @default.
- W566853810 hasConcept C2778004101 @default.
- W566853810 hasConcept C2778078955 @default.
- W566853810 hasConcept C2779134260 @default.
- W566853810 hasConcept C2780479503 @default.
- W566853810 hasConcept C43617362 @default.
- W566853810 hasConcept C55493867 @default.
- W566853810 hasConcept C71924100 @default.
- W566853810 hasConcept C98274493 @default.
- W566853810 hasConceptScore W566853810C126322002 @default.
- W566853810 hasConceptScore W566853810C179998833 @default.
- W566853810 hasConceptScore W566853810C181199279 @default.
- W566853810 hasConceptScore W566853810C185592680 @default.
- W566853810 hasConceptScore W566853810C2775838275 @default.
- W566853810 hasConceptScore W566853810C2775862500 @default.
- W566853810 hasConceptScore W566853810C2776918747 @default.
- W566853810 hasConceptScore W566853810C2778004101 @default.
- W566853810 hasConceptScore W566853810C2778078955 @default.
- W566853810 hasConceptScore W566853810C2779134260 @default.
- W566853810 hasConceptScore W566853810C2780479503 @default.
- W566853810 hasConceptScore W566853810C43617362 @default.
- W566853810 hasConceptScore W566853810C55493867 @default.
- W566853810 hasConceptScore W566853810C71924100 @default.
- W566853810 hasConceptScore W566853810C98274493 @default.
- W566853810 hasLocation W5668538101 @default.
- W566853810 hasLocation W5668538102 @default.
- W566853810 hasOpenAccess W566853810 @default.
- W566853810 hasPrimaryLocation W5668538101 @default.
- W566853810 hasRelatedWork W1963789815 @default.
- W566853810 hasRelatedWork W2083523365 @default.
- W566853810 hasRelatedWork W2349998777 @default.
- W566853810 hasRelatedWork W2356866277 @default.
- W566853810 hasRelatedWork W2368767227 @default.
- W566853810 hasRelatedWork W2726956030 @default.
- W566853810 hasRelatedWork W2793406199 @default.
- W566853810 hasRelatedWork W2980353326 @default.
- W566853810 hasRelatedWork W3039391368 @default.
- W566853810 hasRelatedWork W2417648918 @default.
- W566853810 isParatext "false" @default.
- W566853810 isRetracted "false" @default.
- W566853810 magId "566853810" @default.
- W566853810 workType "article" @default.