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• W568811952 startingPage "e0126882" @default.
• W568811952 abstract "Little is known about the tolerability of antihypertensive drugs during hemodialysis treatment. The present study evaluated the use of the angiotensin II receptor blocker (ARB) irbesartan.Randomized, double-blind, placebo-controlled, one-year intervention trial.Eighty-two hemodialysis patients with urine output >300 mL/day and dialysis vintage <1 year.Irbesartan/placebo 300 mg/day for 12 months administered as add-on to antihypertensive treatment using a predialytic systolic blood pressure target of 140 mmHg in all patients.Cardiac output, stroke volume, central blood volume, total peripheral resistance, mean arterial blood pressure, and frequency of intradialytic hypotension.At baseline, the groups were similar regarding age, comorbidity, blood pressure, antihypertensive medication, ultrafiltration volume, and dialysis parameters. Over the one-year period, predialytic systolic blood pressure decreased significantly, but similarly in both groups. Mean start and mean end cardiac output, stroke volume, total peripheral resistance, heart rate, and mean arterial pressure were stable and similar in the two groups, whereas central blood volume increased slightly but similarly over time. The mean hemodynamic response observed during a dialysis session was a drop in cardiac output, in stroke volume, in mean arterial pressure, and in central blood volume, whereas heart rate increased. Total peripheral resistance did not change significantly. Overall, this pattern remained stable over time in both groups and was uninfluenced by ARB treatment. The total number of intradialytic hypotensive episodes was (placebo/ARB) 50/63 (P = 0.4). Ultrafiltration volume, left ventricular mass index, plasma albumin, and change in intradialytic total peripheral resistance were significantly associated with intradialytic hypotension in a multivariate logistic regression analysis based on baseline parameters.Use of the ARB irbesartan as an add-on to other antihypertensive therapy did not significantly affect intradialytic hemodynamics, neither in short nor long-term, and no significant increase in hypotensive episodes was seen.Clinicaltrials.gov NCT00791830." @default.
• W568811952 created "2016-06-24" @default.
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• W568811952 date "2015-06-01" @default.
• W568811952 modified "2023-09-27" @default.
• W568811952 title "Short and Long-Term Effects of the Angiotensin II Receptor Blocker Irbesartan on Intradialytic Central Hemodynamics: A Randomized Double-Blind Placebo-Controlled One-Year Intervention Trial (the SAFIR Study)" @default.
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• W568811952 cites W1973627491 @default.
• W568811952 cites W1985896094 @default.
• W568811952 cites W1995928910 @default.
• W568811952 cites W1998708696 @default.
• W568811952 cites W2014000236 @default.
• W568811952 cites W2016591900 @default.
• W568811952 cites W2022608799 @default.
• W568811952 cites W2030235211 @default.
• W568811952 cites W2031539613 @default.
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• W568811952 cites W2036960544 @default.
• W568811952 cites W2039354600 @default.
• W568811952 cites W2042897073 @default.
• W568811952 cites W2042934434 @default.
• W568811952 cites W2044562410 @default.
• W568811952 cites W2048928355 @default.
• W568811952 cites W2054121448 @default.
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• W568811952 cites W2086923077 @default.
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• W568811952 doi "https://doi.org/10.1371/journal.pone.0126882" @default.
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