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- W56896514 abstract "For much of the past 30 years, research on the effects of chemical pollution on the environment has focused almost exclusively on ‘conventional’ priority pollutants. However, during the past several years, there has been a growing level of concern related to the hypothesis that various chemicals may exhibit endocrine-disrupting effects. The presence, for example, of steroid hormones and pharmaceuticals in wastewater treatment plant effluents, receiving waters, drinking and groundwater has become an emerging issue of great interest, although it is probable that these compounds have been entering surface- and groundwater systems for as long as people have been using them. The emerging interest is due to increased incidences of endocrine-related diseases in humans, including declining male fertility, and more significantly, to adverse physiological effects observed in wildlife, where cause and effect relationships are more evident. Pharmaceutical-residue analysis is a clear example of improvement in analytical techniques in recent years. In this respect, following appropriate sample preparation, scientists can at present detect nanogram per liter of such active compounds in waters. Pharmaceuticals considered as pseudopersistent pollutants enter the environment at very low concentrations but on a continuous basis. Therefore, the recent advances in their analysis and quantification down to the nanolevels are quite important for the protection of the environment. These techniques include solid phase extraction (SPE), solid phase microextraction (SPME), gas chromatography (GC) tandem mass spectrometry (MS), liquid chromatography (LC) tandem MS, ultraperformance liquid chromatography (UPLC), and quadrupole ion trap-time-of-flight (Q-TOF)." @default.
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- W56896514 date "2011-01-01" @default.
- W56896514 modified "2023-09-25" @default.
- W56896514 title "Advances in Analytical Methods for the Determination of Pharmaceutical Residues in Waters and Wastewaters" @default.
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