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- W56957798 abstract "In addition to its role as the major excitatory neurotransmitter, L-glutamate may have a toxic effect on neurons (Olney et al. 1971). This neurotoxic action depends on a multiplicity of factors such as concentration, exposure period, glutamate receptor expression, and a variety of intracellular events, the exact nature of which is not known. However, it is likely that different second messenger systems such as the inositol phosphates, cGMP and the intracellular Ca++ concentration are of pivotal importance for initiation and propagation of reactions leading to neuronal damage and death (Siesjö 1988; Siesjö et al. 1989; Choi 1988). It is known that cerebral ischemia leads to loss of particular neurons (Ito et al. 1975) and it has been suggested that neurotransmitter glutamate could play a role in this neuronal degeneration (Jørgensen and Diemer 1982). In keeping with this, a variety of pathological conditions such as ischemia and hypoglycemia have been shown to be associated with an overflow of glutamate into the extracellular space in the brain (Benveniste et al. 1984; Drejer et al. 1985; Sandberg et al. 1986). That glutamate may indeed play an important role in ischemic brain damage is underlined by the finding that such damage to hippocampal CA1 pyramidal cells can be prevented by preischemic destruction of glutamatergic dentate gyrus granule cells (Johansen et al. 1986). Moreover, anoxic neuronal death in hippocampal cultures can be prevented by glutamate antagonists (Rothman 1984)." @default.
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- W56957798 date "1991-01-01" @default.
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- W56957798 title "Excitatory Amino Acid Induced Cytotoxicity in Cultured Neurons: Role of Intracellular Ca++ Homeostasis" @default.
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- W56957798 cites W1561097263 @default.
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- W56957798 cites W1636078186 @default.
- W56957798 cites W1644418226 @default.
- W56957798 cites W1890213598 @default.
- W56957798 cites W1957958801 @default.
- W56957798 cites W1964562899 @default.
- W56957798 cites W1966428196 @default.
- W56957798 cites W1966751481 @default.
- W56957798 cites W1967113275 @default.
- W56957798 cites W1968954692 @default.
- W56957798 cites W1971502696 @default.
- W56957798 cites W1976242105 @default.
- W56957798 cites W1977201296 @default.
- W56957798 cites W1977938288 @default.
- W56957798 cites W1978030967 @default.
- W56957798 cites W1978507389 @default.
- W56957798 cites W1979992200 @default.
- W56957798 cites W1981550729 @default.
- W56957798 cites W1984449008 @default.
- W56957798 cites W1985053181 @default.
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- W56957798 cites W1994322539 @default.
- W56957798 cites W1997611160 @default.
- W56957798 cites W1997636328 @default.
- W56957798 cites W2004603947 @default.
- W56957798 cites W2005077264 @default.
- W56957798 cites W2005599435 @default.
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- W56957798 cites W2007536583 @default.
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- W56957798 cites W2021729913 @default.
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- W56957798 cites W2026660727 @default.
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- W56957798 cites W2039574372 @default.
- W56957798 cites W2039605179 @default.
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- W56957798 cites W2139748951 @default.
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- W56957798 cites W21757144 @default.
- W56957798 cites W3002740628 @default.
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- W56957798 doi "https://doi.org/10.1007/978-3-642-84526-0_12" @default.
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