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- W56988934 abstract "443 Objectives Recently introduced ultrafast cardiac SPECT cameras (UFC) with cadmium zinc telluride-based (CZT) detectors may combine reduced scan times with improved diagnostic images. We compared a conventional SPECT-CT with a CZT-based SPECT-CT scanner, with regard to the need for additional tests after initial stress testing with both cameras. Methods 447 stable patients without known Coronary Artery Disease (CAD) and low-intermediate pre-test likelihood, were referred for non-invasive detection of CAD by a hybrid SPECT-CT (64-slice) scanner using an individualized stepwise decision algorithm. Low dose stress-SPECT was used as screenings test, only followed by additional rest imaging and/or CT coronary angiography in case of perfusion abnormalities. A total of 224 patients underwent SPECT-CT imaging with a conventional SPECT-CT scanner (Ventri-LightSpeed VCT XT, GE Healthcare) and 223 patients had SPECT-CT imaging with a CZT-based SPECT-CT scanner (Discovery NM/CT 570, GE Healthcare). Results There were no differences between the 2 cohorts in demographic and baseline characteristics or pre-test likelihood of CAD. Mean (± SD) age was 60 (11) years, 48% were male. The 223 patients scanned by the new camera required less downstream testing by additional rest-SPECT and/or CT coronary angiography, 35% versus 55% (p Conclusions Implementation of a new ultrafast cardiac SPECT camera resulted in a significant decrease in need for additional tests, with lower radiation exposure. Long-term follow-up studies should prove the diagnostic accuracy and safety of the new camera" @default.
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- W56988934 date "2011-05-01" @default.
- W56988934 modified "2023-10-18" @default.
- W56988934 title "Clinical implications of a new ultrafast SPECT camera for detecting myocardial ischemia in stable patients" @default.
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