Matches in SemOpenAlex for { <https://semopenalex.org/work/W570439084> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W570439084 abstract "Different multiple-injection methodologies and the partial filling technique (PFT) have been utilized for separation of pharmaceuticals by capillary elec-trophoresis. In multiple-injection capillary zone electrophoresis (MICZE), the samples and all standards, used for construction of the calibration curve, are analyzed within a single run. Four different modes of MICZE have been described by means of equations, which were experimentally verified. The developed equations facilitate the transfer from conventional single-injection CZE to one or more of these MICZE-modes, depending on the selectivity between the analyte and the injection marker. The applicability of two of these modes was then demonstrated by quantification of buserelin and salbutamol, re-spectively in commercially available pharmaceutical products. The content of buserelin in an injection solution was determined to 0.94 mg/ml, which only deviated slightly from the declared concentration (1 mg/ml). An alter-native mode of MICZE, offering a higher number of sequential sample injec-tions, was then utilized for single-run determination of salbutamol in 15 tab-lets, with a labelled content of 8 mg. The average content of the tablets was determined to 7.8 mg, with an intra-tablet variation of 3 % or less. Moreover, UV- and mass-spectrometric detection of enantiomeric amines, resolved by non-aqueous capillary electrophoresis (NACE), was demon-strated. Separation of enantiomeric amines was achieved using the chiral selector (-)-2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid, (-)-DIKGA. Introduction of the non-volatile (-)-DIKGA into the mass-spectrometer was avoided by using the PFT, where the capillary is only partially filled with electrolyte containing the chiral selector." @default.
- W570439084 created "2016-06-24" @default.
- W570439084 creator A5021199221 @default.
- W570439084 creator A5024319019 @default.
- W570439084 creator A5068279623 @default.
- W570439084 creator A5087949539 @default.
- W570439084 date "2008-01-01" @default.
- W570439084 modified "2023-09-27" @default.
- W570439084 title "Determination of Salbutamol in Tablets by Multiple-injection Capillary Zone Electrophoresis" @default.
- W570439084 hasPublicationYear "2008" @default.
- W570439084 type Work @default.
- W570439084 sameAs 570439084 @default.
- W570439084 citedByCount "0" @default.
- W570439084 crossrefType "journal-article" @default.
- W570439084 hasAuthorship W570439084A5021199221 @default.
- W570439084 hasAuthorship W570439084A5024319019 @default.
- W570439084 hasAuthorship W570439084A5068279623 @default.
- W570439084 hasAuthorship W570439084A5087949539 @default.
- W570439084 hasConcept C10390740 @default.
- W570439084 hasConcept C106487976 @default.
- W570439084 hasConcept C113196181 @default.
- W570439084 hasConcept C119128265 @default.
- W570439084 hasConcept C159985019 @default.
- W570439084 hasConcept C185592680 @default.
- W570439084 hasConcept C192562407 @default.
- W570439084 hasConcept C196806460 @default.
- W570439084 hasConcept C23531484 @default.
- W570439084 hasConcept C2900643 @default.
- W570439084 hasConcept C43617362 @default.
- W570439084 hasConcept C486523 @default.
- W570439084 hasConcept C71240020 @default.
- W570439084 hasConceptScore W570439084C10390740 @default.
- W570439084 hasConceptScore W570439084C106487976 @default.
- W570439084 hasConceptScore W570439084C113196181 @default.
- W570439084 hasConceptScore W570439084C119128265 @default.
- W570439084 hasConceptScore W570439084C159985019 @default.
- W570439084 hasConceptScore W570439084C185592680 @default.
- W570439084 hasConceptScore W570439084C192562407 @default.
- W570439084 hasConceptScore W570439084C196806460 @default.
- W570439084 hasConceptScore W570439084C23531484 @default.
- W570439084 hasConceptScore W570439084C2900643 @default.
- W570439084 hasConceptScore W570439084C43617362 @default.
- W570439084 hasConceptScore W570439084C486523 @default.
- W570439084 hasConceptScore W570439084C71240020 @default.
- W570439084 hasLocation W5704390841 @default.
- W570439084 hasOpenAccess W570439084 @default.
- W570439084 hasPrimaryLocation W5704390841 @default.
- W570439084 hasRelatedWork W1546387002 @default.
- W570439084 hasRelatedWork W1560054301 @default.
- W570439084 hasRelatedWork W1569813981 @default.
- W570439084 hasRelatedWork W1980409192 @default.
- W570439084 hasRelatedWork W1981464855 @default.
- W570439084 hasRelatedWork W1991288919 @default.
- W570439084 hasRelatedWork W2023944700 @default.
- W570439084 hasRelatedWork W2054827224 @default.
- W570439084 hasRelatedWork W2061707623 @default.
- W570439084 hasRelatedWork W2064318433 @default.
- W570439084 hasRelatedWork W2103461197 @default.
- W570439084 hasRelatedWork W2107157966 @default.
- W570439084 hasRelatedWork W2147241390 @default.
- W570439084 hasRelatedWork W2258961509 @default.
- W570439084 hasRelatedWork W2386170582 @default.
- W570439084 hasRelatedWork W2462458534 @default.
- W570439084 hasRelatedWork W2665709440 @default.
- W570439084 hasRelatedWork W2920185062 @default.
- W570439084 hasRelatedWork W3178181339 @default.
- W570439084 hasRelatedWork W2181506244 @default.
- W570439084 isParatext "false" @default.
- W570439084 isRetracted "false" @default.
- W570439084 magId "570439084" @default.
- W570439084 workType "article" @default.