FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W57052898> ?p ?o ?g. }

• W57052898 abstract "BACKGROUND There have been no studies evaluating the efficacy and potential risks of stronger neo-minophagen C (SNMC) in pregnant women with chronic hepatitis B CHB. MATERIAL/METHODS A total of 36 pregnant women with CHB, but without severe complications, were randomized to intravenously receive SNMC or S-adenosyl-L-methionine (SAM) daily for 4 weeks or until birth. Normalization of serum alanine transaminase (ALT) and aspartate transaminase (AST) levels and changes in ALT and AST levels from baseline were determined. All neonates were regularly examined for up to 1 year. RESULTS Treatment with SNMC and SAM resulted in normalization of ALT levels at 4 weeks in 64.3% and 21.4% of patients, respectively (OR=6.60, 95% CI: 1.23-35.44, P=0.0540). SNMC and SAM significantly decreased ALT (from 558.28+/-390.24 to 47.07+/-24.94 IU/L, P<0.0001 and from 525.61+/-483.87 to 117.43+/-85.44 IU/L, P=0.0041, respectively) and AST (from 419.72+/-409.49 to 38.14+/-18.87 IU/L, P=0.0016, and from 510.78+/-621.58 to 79.93+/-63.25 IU/L, P=0.0152, respectively) at 4 weeks relative to baseline values. Hypokalemia was observed in 4 SNMC-treated patients and in 2 SAM-treated patients and hypernatremia in 3 SNMC-treated and in 3 SAM-treated patients. Hypertension was observed in 1 SNMC-treated patient. There was no significant difference in the volume of amniotic fluid or meconium between SNMC-treated and SAM-treated groups. All the neonates were physically normal at birth and at the 1-year follow-up examination. CONCLUSIONS Both SNMC and SAM improve liver function, with SNMC appearing more effective, in pregnant women with chronic hepatitis B without impact on fetal development." @default.
• W57052898 created "2016-06-24" @default.
• W57052898 creator A5029047259 @default.
• W57052898 creator A5032884837 @default.
• W57052898 creator A5033713296 @default.
• W57052898 creator A5040967386 @default.
• W57052898 creator A5041439110 @default.
• W57052898 creator A5049061801 @default.
• W57052898 creator A5052919065 @default.
• W57052898 creator A5068507164 @default.
• W57052898 creator A5074112736 @default.
• W57052898 creator A5078897068 @default.
• W57052898 date "2010-08-01" @default.
• W57052898 modified "2023-10-12" @default.
• W57052898 title "Efficacy and safety of intravenous stronger neo-minophagen C and S-adenosyl-L-methionine in treatment of pregnant woman with chronic hepatitis B: a pilot study." @default.
• W57052898 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20671623" @default.
• W57052898 hasPublicationYear "2010" @default.
• W57052898 type Work @default.
• W57052898 sameAs 57052898 @default.
• W57052898 citedByCount "2" @default.
• W57052898 countsByYear W570528982015 @default.
• W57052898 countsByYear W570528982017 @default.
• W57052898 crossrefType "journal-article" @default.
• W57052898 hasAuthorship W57052898A5029047259 @default.
• W57052898 hasAuthorship W57052898A5032884837 @default.
• W57052898 hasAuthorship W57052898A5033713296 @default.
• W57052898 hasAuthorship W57052898A5040967386 @default.
• W57052898 hasAuthorship W57052898A5041439110 @default.
• W57052898 hasAuthorship W57052898A5049061801 @default.
• W57052898 hasAuthorship W57052898A5052919065 @default.
• W57052898 hasAuthorship W57052898A5068507164 @default.
• W57052898 hasAuthorship W57052898A5074112736 @default.
• W57052898 hasAuthorship W57052898A5078897068 @default.
• W57052898 hasConcept C126322002 @default.
• W57052898 hasConcept C160160445 @default.
• W57052898 hasConcept C172680121 @default.
• W57052898 hasConcept C181199279 @default.
• W57052898 hasConcept C185592680 @default.
• W57052898 hasConcept C2776877979 @default.
• W57052898 hasConcept C2777382497 @default.
• W57052898 hasConcept C2777785397 @default.
• W57052898 hasConcept C2778194526 @default.
• W57052898 hasConcept C2778242168 @default.
• W57052898 hasConcept C2778606649 @default.
• W57052898 hasConcept C2779234561 @default.
• W57052898 hasConcept C2779679107 @default.
• W57052898 hasConcept C2780985857 @default.
• W57052898 hasConcept C54355233 @default.
• W57052898 hasConcept C55493867 @default.
• W57052898 hasConcept C71924100 @default.
• W57052898 hasConcept C86803240 @default.
• W57052898 hasConcept C90924648 @default.
• W57052898 hasConceptScore W57052898C126322002 @default.
• W57052898 hasConceptScore W57052898C160160445 @default.
• W57052898 hasConceptScore W57052898C172680121 @default.
• W57052898 hasConceptScore W57052898C181199279 @default.
• W57052898 hasConceptScore W57052898C185592680 @default.
• W57052898 hasConceptScore W57052898C2776877979 @default.
• W57052898 hasConceptScore W57052898C2777382497 @default.
• W57052898 hasConceptScore W57052898C2777785397 @default.
• W57052898 hasConceptScore W57052898C2778194526 @default.
• W57052898 hasConceptScore W57052898C2778242168 @default.
• W57052898 hasConceptScore W57052898C2778606649 @default.
• W57052898 hasConceptScore W57052898C2779234561 @default.
• W57052898 hasConceptScore W57052898C2779679107 @default.
• W57052898 hasConceptScore W57052898C2780985857 @default.
• W57052898 hasConceptScore W57052898C54355233 @default.
• W57052898 hasConceptScore W57052898C55493867 @default.
• W57052898 hasConceptScore W57052898C71924100 @default.
• W57052898 hasConceptScore W57052898C86803240 @default.
• W57052898 hasConceptScore W57052898C90924648 @default.
• W57052898 hasIssue "8" @default.
• W57052898 hasLocation W570528981 @default.
• W57052898 hasLocation W570528982 @default.
• W57052898 hasOpenAccess W57052898 @default.
• W57052898 hasPrimaryLocation W570528981 @default.
• W57052898 hasRelatedWork W2148204453 @default.
• W57052898 hasRelatedWork W2170907313 @default.
• W57052898 hasRelatedWork W2293622767 @default.
• W57052898 hasRelatedWork W2347605214 @default.
• W57052898 hasRelatedWork W2348816739 @default.
• W57052898 hasRelatedWork W2353896645 @default.
• W57052898 hasRelatedWork W2363268045 @default.
• W57052898 hasRelatedWork W2363717692 @default.
• W57052898 hasRelatedWork W2365543306 @default.
• W57052898 hasRelatedWork W2372542253 @default.
• W57052898 hasRelatedWork W2373124390 @default.
• W57052898 hasRelatedWork W2374400649 @default.
• W57052898 hasRelatedWork W2375439660 @default.
• W57052898 hasRelatedWork W2377379263 @default.
• W57052898 hasRelatedWork W2384621587 @default.
• W57052898 hasRelatedWork W2387005592 @default.
• W57052898 hasRelatedWork W2392683998 @default.
• W57052898 hasRelatedWork W2411066356 @default.
• W57052898 hasRelatedWork W2598757153 @default.
• W57052898 hasRelatedWork W2966413686 @default.
• W57052898 hasVolume "16" @default.
• W57052898 isParatext "false" @default.
• W57052898 isRetracted "false" @default.
• W57052898 magId "57052898" @default.

• next