Matches in SemOpenAlex for { <https://semopenalex.org/work/W57083323> ?p ?o ?g. }
- W57083323 endingPage "80" @default.
- W57083323 startingPage "175" @default.
- W57083323 abstract "Lima, Peru.To describe drug resistance profiles of TB isolates from patients at risk for multidrug-resistant tuberculosis (MDR-TB), and to consider the implications of these findings for treatment.Descriptive study of drug susceptibility testing (DST) results for TB isolates from 1680 patients referred for suspicion of MDR-TB between 1996 and 2001.Of 1680 isolates tested, 1144 (68%) were resistant to at least one anti-tuberculosis drug and 926 (55%) were MDR-TB strains. Of 926 MDR isolates, 50 (5%) were resistant to INH and RMP alone, while 367 (40%) were resistant to at least five first-line drugs. We identified 146 unique drug resistance profiles, the most common of which accounted for 11% of drug-resistant isolates. The annual prevalence of isolates with resistance to at least five first-line drugs rose significantly during the study period, from 29% to 37% (P = 0.00086).This is a group of patients with TB disease among whom the prevalence of a broad spectrum of often highly drug-resistant strains appears to be increasing over time. A single standardized retreatment regimen may be inadequate to cure most patients. Capacity for drug sensitivity testing is essential for development of multiple standardized retreatment or individualized treatment regimens and epidemiological surveillance for planning." @default.
- W57083323 created "2016-06-24" @default.
- W57083323 creator A5000757708 @default.
- W57083323 creator A5008882338 @default.
- W57083323 creator A5022727173 @default.
- W57083323 creator A5044748105 @default.
- W57083323 creator A5064304201 @default.
- W57083323 creator A5082730150 @default.
- W57083323 creator A5082838260 @default.
- W57083323 date "2005-02-01" @default.
- W57083323 modified "2023-10-17" @default.
- W57083323 title "Drug resistance profiles of Mycobacterium tuberculosis isolates: five years' experience and insight into treatment strategies for MDR-TB in Lima, Peru." @default.
- W57083323 cites W1980090298 @default.
- W57083323 cites W2003810398 @default.
- W57083323 cites W2043453176 @default.
- W57083323 cites W2043903214 @default.
- W57083323 cites W2064943876 @default.
- W57083323 cites W2089465091 @default.
- W57083323 cites W2092376949 @default.
- W57083323 cites W2094966261 @default.
- W57083323 cites W2116143648 @default.
- W57083323 cites W2124127309 @default.
- W57083323 cites W2130718830 @default.
- W57083323 cites W2131064431 @default.
- W57083323 cites W2137884414 @default.
- W57083323 cites W2139217634 @default.
- W57083323 cites W2144362977 @default.
- W57083323 cites W2164403160 @default.
- W57083323 cites W2167575493 @default.
- W57083323 cites W2338591221 @default.
- W57083323 cites W2410325834 @default.
- W57083323 cites W2413782556 @default.
- W57083323 cites W2416261459 @default.
- W57083323 cites W2735151752 @default.
- W57083323 cites W67148332 @default.
- W57083323 cites W84129908 @default.
- W57083323 cites W1997662775 @default.
- W57083323 cites W2290744817 @default.
- W57083323 cites W2883238846 @default.
- W57083323 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15732737" @default.
- W57083323 hasPublicationYear "2005" @default.
- W57083323 type Work @default.
- W57083323 sameAs 57083323 @default.
- W57083323 citedByCount "7" @default.
- W57083323 countsByYear W570833232016 @default.
- W57083323 countsByYear W570833232022 @default.
- W57083323 crossrefType "journal-article" @default.
- W57083323 hasAuthorship W57083323A5000757708 @default.
- W57083323 hasAuthorship W57083323A5008882338 @default.
- W57083323 hasAuthorship W57083323A5022727173 @default.
- W57083323 hasAuthorship W57083323A5044748105 @default.
- W57083323 hasAuthorship W57083323A5064304201 @default.
- W57083323 hasAuthorship W57083323A5082730150 @default.
- W57083323 hasAuthorship W57083323A5082838260 @default.
- W57083323 hasConcept C107130276 @default.
- W57083323 hasConcept C114851261 @default.
- W57083323 hasConcept C126322002 @default.
- W57083323 hasConcept C133936738 @default.
- W57083323 hasConcept C142724271 @default.
- W57083323 hasConcept C2777107064 @default.
- W57083323 hasConcept C2777975735 @default.
- W57083323 hasConcept C2780035454 @default.
- W57083323 hasConcept C2781069245 @default.
- W57083323 hasConcept C2781413609 @default.
- W57083323 hasConcept C71924100 @default.
- W57083323 hasConcept C86803240 @default.
- W57083323 hasConcept C89423630 @default.
- W57083323 hasConcept C98274493 @default.
- W57083323 hasConceptScore W57083323C107130276 @default.
- W57083323 hasConceptScore W57083323C114851261 @default.
- W57083323 hasConceptScore W57083323C126322002 @default.
- W57083323 hasConceptScore W57083323C133936738 @default.
- W57083323 hasConceptScore W57083323C142724271 @default.
- W57083323 hasConceptScore W57083323C2777107064 @default.
- W57083323 hasConceptScore W57083323C2777975735 @default.
- W57083323 hasConceptScore W57083323C2780035454 @default.
- W57083323 hasConceptScore W57083323C2781069245 @default.
- W57083323 hasConceptScore W57083323C2781413609 @default.
- W57083323 hasConceptScore W57083323C71924100 @default.
- W57083323 hasConceptScore W57083323C86803240 @default.
- W57083323 hasConceptScore W57083323C89423630 @default.
- W57083323 hasConceptScore W57083323C98274493 @default.
- W57083323 hasIssue "2" @default.
- W57083323 hasLocation W570833231 @default.
- W57083323 hasOpenAccess W57083323 @default.
- W57083323 hasPrimaryLocation W570833231 @default.
- W57083323 hasRelatedWork W1979047406 @default.
- W57083323 hasRelatedWork W1980108230 @default.
- W57083323 hasRelatedWork W2063314392 @default.
- W57083323 hasRelatedWork W2127258416 @default.
- W57083323 hasRelatedWork W2155954588 @default.
- W57083323 hasRelatedWork W2162580901 @default.
- W57083323 hasRelatedWork W2380511218 @default.
- W57083323 hasRelatedWork W2991542628 @default.
- W57083323 hasRelatedWork W3001165615 @default.
- W57083323 hasRelatedWork W3141580208 @default.
- W57083323 hasVolume "9" @default.
- W57083323 isParatext "false" @default.