Matches in SemOpenAlex for { <https://semopenalex.org/work/W57097576> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W57097576 endingPage "817" @default.
- W57097576 startingPage "813" @default.
- W57097576 abstract "Summary In order to study whether a low molecular weight heparin (LMWH) of mw 4000 D is effective in the treatment of deep venous thrombosis (DVT), patients with DVT verified by phlebography were randomized to treatment by continuous intravenous infusion of either unfractionated heparin (UFH) or LMWH. The initial dose was 240 U (anti F Xa)/kg/12 h. TTiis study (study I) was stopped because of major bleeding in 2 newly operated patients in the LMWH group after 27 patients had been treated. The heparin activity measured as F Xa inhibition assayed in retrospect, was found to be much higher in the LMWH group (mean 1.6-2.0 anti F Xa U/ml) than in the UFH group (mean 0.5-0.8 anti F Xa U/ml). A second study was therefore initiated in which the DVT patients were randomly given UFH (240 U/kg/12 h) or LMWH only 120 U (anti F Xa)/kg/12 h, as initial doses (study II). In this study 27 patients could be evaluated, the mean heparin activity still being higher in the LMWH group (0.9-1.2 anti F Xa U/ml) than in the UFH group (0.5-0.7 anti F Xa U/ml). A second phlebographic investigation showed progression of thrombus size in 3 (11%) of the UFH patients of studies I and II (n = 29) and improvement in 14 (48%). There was no progression in any LMWH patient, 6 (50%) had improved in study I and 10 (77%) in study II. The mean decrease of thrombus size score (according to Marder) during treatment did not differ between the 3 groups. Antithrombin III decreased significantly in the UFH group but not in the LMWH groups. Aminotransferases increased in all 3 groups. There was no difference in mean capillary bleeding time between the 3 treatment groups. Although this material is relatively small, our findings suggest that LMWH seems to be of similar effectivity as UFH." @default.
- W57097576 created "2016-06-24" @default.
- W57097576 creator A5057524553 @default.
- W57097576 creator A5057559196 @default.
- W57097576 creator A5060122149 @default.
- W57097576 creator A5076564718 @default.
- W57097576 creator A5090594462 @default.
- W57097576 date "1985-01-01" @default.
- W57097576 modified "2023-10-16" @default.
- W57097576 title "A Comparison Between Low Molecular Weight Heparin (KABI 2165) and Standard Heparin in the Intravenous Treatment of Deep Venous Thrombosis" @default.
- W57097576 doi "https://doi.org/10.1055/s-0038-1660139" @default.
- W57097576 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3911482" @default.
- W57097576 hasPublicationYear "1985" @default.
- W57097576 type Work @default.
- W57097576 sameAs 57097576 @default.
- W57097576 citedByCount "148" @default.
- W57097576 countsByYear W570975762012 @default.
- W57097576 countsByYear W570975762013 @default.
- W57097576 countsByYear W570975762014 @default.
- W57097576 countsByYear W570975762015 @default.
- W57097576 countsByYear W570975762017 @default.
- W57097576 countsByYear W570975762018 @default.
- W57097576 countsByYear W570975762020 @default.
- W57097576 crossrefType "journal-article" @default.
- W57097576 hasAuthorship W57097576A5057524553 @default.
- W57097576 hasAuthorship W57097576A5057559196 @default.
- W57097576 hasAuthorship W57097576A5060122149 @default.
- W57097576 hasAuthorship W57097576A5076564718 @default.
- W57097576 hasAuthorship W57097576A5090594462 @default.
- W57097576 hasConcept C141071460 @default.
- W57097576 hasConcept C2776884760 @default.
- W57097576 hasConcept C2777557582 @default.
- W57097576 hasConcept C2778205648 @default.
- W57097576 hasConcept C2780011451 @default.
- W57097576 hasConcept C2780868729 @default.
- W57097576 hasConcept C2781362458 @default.
- W57097576 hasConcept C2991741193 @default.
- W57097576 hasConcept C42219234 @default.
- W57097576 hasConcept C71924100 @default.
- W57097576 hasConcept C90924648 @default.
- W57097576 hasConceptScore W57097576C141071460 @default.
- W57097576 hasConceptScore W57097576C2776884760 @default.
- W57097576 hasConceptScore W57097576C2777557582 @default.
- W57097576 hasConceptScore W57097576C2778205648 @default.
- W57097576 hasConceptScore W57097576C2780011451 @default.
- W57097576 hasConceptScore W57097576C2780868729 @default.
- W57097576 hasConceptScore W57097576C2781362458 @default.
- W57097576 hasConceptScore W57097576C2991741193 @default.
- W57097576 hasConceptScore W57097576C42219234 @default.
- W57097576 hasConceptScore W57097576C71924100 @default.
- W57097576 hasConceptScore W57097576C90924648 @default.
- W57097576 hasIssue "04" @default.
- W57097576 hasLocation W570975761 @default.
- W57097576 hasLocation W570975762 @default.
- W57097576 hasOpenAccess W57097576 @default.
- W57097576 hasPrimaryLocation W570975761 @default.
- W57097576 hasRelatedWork W1818791460 @default.
- W57097576 hasRelatedWork W1981597664 @default.
- W57097576 hasRelatedWork W2035403045 @default.
- W57097576 hasRelatedWork W2156414371 @default.
- W57097576 hasRelatedWork W2376273612 @default.
- W57097576 hasRelatedWork W2401972826 @default.
- W57097576 hasRelatedWork W2414818497 @default.
- W57097576 hasRelatedWork W2416233937 @default.
- W57097576 hasRelatedWork W2466300725 @default.
- W57097576 hasRelatedWork W2884482944 @default.
- W57097576 hasVolume "54" @default.
- W57097576 isParatext "false" @default.
- W57097576 isRetracted "false" @default.
- W57097576 magId "57097576" @default.
- W57097576 workType "article" @default.