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- W5714452 abstract "Infective third stage larvae (L3) of Trichostrongylus vitrinus were radiolabelled with 75 selenium by a method which did not affect their viability. Three groups of six-month-old lambs were infected daily with 1000 L3 for four, eight and 12 weeks, respectively. After each period, one of those groups (n = 5) and a group (n = 4) of worm-free controls were challenged with three consecutive daily doses of 1000 radiolabelled L3, killed 10 days after the first dose, and their worm burdens examined. After four weeks of continuous infection partial immunity to the establishment of challenge L3 was apparent, and by eight and 12 weeks, with the exception of one sheep, there was almost total resistance to incoming worms. Immunity was also expressed as an inhibition of the development of established worms." @default.
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- W5714452 date "1989-01-01" @default.
- W5714452 modified "2023-10-16" @default.
- W5714452 title "Development of immunity to incoming radiolabelled larvae in lambs continuously infected with Trichostrongylus vitrinus" @default.
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- W5714452 doi "https://doi.org/10.1016/s0034-5288(18)31111-1" @default.
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