Matches in SemOpenAlex for { <https://semopenalex.org/work/W57203401> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W57203401 endingPage "87" @default.
- W57203401 startingPage "177" @default.
- W57203401 abstract "Mantle cell lymphoma (MCL), which accounts for about 6% of non-Hodgkin lymphoma (NHL), is characterized by the chromosomal translocation t(11;14)(q13;q32), resulting in de-regulated expression of cyclin D1. Managing MCL is challenging, because it is incurable with conventional chemotherapy as with indolent NHL, but has a more aggressive natural history. Therapeutic advances have been made in the past decade with the incorporation of targeted therapies into the frontline setting, use of aggressive combination regimens followed by consolidation with high dose therapy and autologous stem cell rescue for a younger population, use of less aggressive combinations in the elderly, and translation of pre-clinical findings to the clinical trial realm with novel agents that hold significant promise in the treatment of this disease. The authors review current standard approaches in the treatment of MCL, and novel findings in the pathogenesis of this disease that may guide the way for further development of modern therapeutic approaches." @default.
- W57203401 created "2016-06-24" @default.
- W57203401 creator A5010673295 @default.
- W57203401 creator A5089854184 @default.
- W57203401 date "2013-03-01" @default.
- W57203401 modified "2023-09-23" @default.
- W57203401 title "Therapies for mantle cell lymphoma: current challenges and a brighter future." @default.
- W57203401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23545046" @default.
- W57203401 hasPublicationYear "2013" @default.
- W57203401 type Work @default.
- W57203401 sameAs 57203401 @default.
- W57203401 citedByCount "1" @default.
- W57203401 countsByYear W572034012015 @default.
- W57203401 crossrefType "journal-article" @default.
- W57203401 hasAuthorship W57203401A5010673295 @default.
- W57203401 hasAuthorship W57203401A5089854184 @default.
- W57203401 hasConcept C121608353 @default.
- W57203401 hasConcept C126322002 @default.
- W57203401 hasConcept C143998085 @default.
- W57203401 hasConcept C177713679 @default.
- W57203401 hasConcept C199835354 @default.
- W57203401 hasConcept C2777525834 @default.
- W57203401 hasConcept C2779134260 @default.
- W57203401 hasConcept C2779338263 @default.
- W57203401 hasConcept C2908647359 @default.
- W57203401 hasConcept C29537977 @default.
- W57203401 hasConcept C502942594 @default.
- W57203401 hasConcept C535046627 @default.
- W57203401 hasConcept C71924100 @default.
- W57203401 hasConcept C99454951 @default.
- W57203401 hasConceptScore W57203401C121608353 @default.
- W57203401 hasConceptScore W57203401C126322002 @default.
- W57203401 hasConceptScore W57203401C143998085 @default.
- W57203401 hasConceptScore W57203401C177713679 @default.
- W57203401 hasConceptScore W57203401C199835354 @default.
- W57203401 hasConceptScore W57203401C2777525834 @default.
- W57203401 hasConceptScore W57203401C2779134260 @default.
- W57203401 hasConceptScore W57203401C2779338263 @default.
- W57203401 hasConceptScore W57203401C2908647359 @default.
- W57203401 hasConceptScore W57203401C29537977 @default.
- W57203401 hasConceptScore W57203401C502942594 @default.
- W57203401 hasConceptScore W57203401C535046627 @default.
- W57203401 hasConceptScore W57203401C71924100 @default.
- W57203401 hasConceptScore W57203401C99454951 @default.
- W57203401 hasIssue "82" @default.
- W57203401 hasLocation W572034011 @default.
- W57203401 hasOpenAccess W57203401 @default.
- W57203401 hasPrimaryLocation W572034011 @default.
- W57203401 hasRelatedWork W102554310 @default.
- W57203401 hasRelatedWork W1969504315 @default.
- W57203401 hasRelatedWork W1972550354 @default.
- W57203401 hasRelatedWork W2106342544 @default.
- W57203401 hasRelatedWork W2415533234 @default.
- W57203401 hasRelatedWork W2610360477 @default.
- W57203401 hasRelatedWork W2979960296 @default.
- W57203401 hasRelatedWork W3028980024 @default.
- W57203401 hasRelatedWork W3030318556 @default.
- W57203401 hasRelatedWork W4200092732 @default.
- W57203401 hasVolume "15" @default.
- W57203401 isParatext "false" @default.
- W57203401 isRetracted "false" @default.
- W57203401 magId "57203401" @default.
- W57203401 workType "article" @default.