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- W573371772 abstract "The analysis of pathological gait using musculoskeletal modeling is a promising approach to qualify and quantify the pathology as well as to monitor the potential recovery after therapy. When dealing with cerebral palsy, its specific neurological disorders and consequently bones deformities, specific-subject musculoskeletal models has been developed. The imaging techniques are still unaffordable in clinical practises. So, using the LifeMod software, we aimed to develop musculoskeletal model in a retrospective study to evaluate the accuracy of surgical treatments on cerebral palsy. Two principles studies are performed. First, relying on the accuracy of a rescaled generic adult skeleton, the musculoskeletal modeling limitation have been determined when applying normal gait and pathological crouch and jump postures, imitated by healthy adults and children. Second, calibration technique had been developed to refine the model’s parameters based on data collectid from the subject. Results from musculoskeletal modeling are compared to gait analysis date. As results, even if the model outputs gave correct results with healthy adults, the standard rescaled musculoskeletal modeling showed limits on predicted kinematics and muscle forces for healthy and CP children. The refinement of subject-specific joint parameters and driving the model with the experimental GRF data have a huge influence in model outputs and improve quantitatively the predicted muscle activations and forces. This work pointed out that the parameters of a rescaled generic musculoskeletal moded can be refined and personalized to improve model’s outcomes. It may represent a new perspective in clinical applications." @default.
- W573371772 created "2016-06-24" @default.
- W573371772 creator A5067270311 @default.
- W573371772 date "2012-01-01" @default.
- W573371772 modified "2023-09-26" @default.
- W573371772 title "Musculoskeletal modeling of cerebral palsy children" @default.
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