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- W57389721 abstract "Publisher Summary Today, many clinical applications rely on medical imaging. Disease diagnosis, therapy planning, and surgical operations are often supported by several imaging modalities, providing complementary information. This chapter discusses a novel method called neuroslicer for accurate registration of autoradiographs of rat brain to a standard atlas. Atlas is a general term used to refer to a framework, derived from either a single representative brain or an average anatomic template. The 3-D surface atlas is created based on two-dimensional cryosection images, which are used as reference maps for the rat brain. The surface is resliced into new sections with the resolution high enough to cover a wide range of sectioning angles for experimental brains. Shape matching and transforming from sample data to the atlas is performed by using the thin plate spline model. This chapter reviews intrasubject image matching, intersubject image matching, and the neuroslicer. The problem of intrasubject cross modality registration is more difficult because of the modality-specific inconsistencies between images, such as incomplete coverage, intensity distortions, geometric distortions, and lack of contrast. Quantitative analysis of autoradiographic data helps neuroscientists to determine the functional properties of a particular region." @default.
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- W57389721 date "2001-01-01" @default.
- W57389721 modified "2023-09-27" @default.
- W57389721 title "Neuro Slicer" @default.
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- W57389721 doi "https://doi.org/10.1016/b978-012059781-9/50014-6" @default.
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