Matches in SemOpenAlex for { <https://semopenalex.org/work/W57548255> ?p ?o ?g. }
- W57548255 endingPage "174" @default.
- W57548255 startingPage "111" @default.
- W57548255 abstract "The role of the serotonergic system in the neuroplastic events that create, repair, and degenerate the brain has been explored. Synaptic plasticity occurs throughout life and is critical during brain development. Evidence from biochemical, pharmacological, and clinical studies demonstrates the huge importance of an intact serotonergic system for normal central nervous system (CNS)function. Serotonin acts as a growth factor during embryogenesis, and serotonin receptor activity forms a crucial part of the cascade of events leading to changes in brain structure. The serotonergic system interacts with brain-derived neurotrophic factor (BDNF), S100beta, and other chemical messengers, in addition to ts cross talk with the GABAergic, glutamatergic, and dopaminergic neurotransmitter systems. Disruption of these processes may contribute to CNS disorders that have been associated with impaired development. Furthermore, many psychiatric drugs alter serotonergic activity and have been shown to create changes in brain structure with long-term treatment. However, the mechanisms for their therapeutic efficacy are still unclear. Treatments for psychiatric illness are usually chronic and alleviate psychiatric symptoms, rather than cure these diseases. Therefore, greater exploration of the serotonin system during brain development and growth could lead to real progress in the discovery of treatments for mental disorders." @default.
- W57548255 created "2016-06-24" @default.
- W57548255 creator A5082321134 @default.
- W57548255 creator A5087737932 @default.
- W57548255 date "2004-01-01" @default.
- W57548255 modified "2023-10-18" @default.
- W57548255 title "Serotonin and brain development" @default.
- W57548255 cites W11368365 @default.
- W57548255 cites W114055788 @default.
- W57548255 cites W1422618495 @default.
- W57548255 cites W14681528 @default.
- W57548255 cites W1482645631 @default.
- W57548255 cites W1483057098 @default.
- W57548255 cites W1487053105 @default.
- W57548255 cites W1488923896 @default.
- W57548255 cites W1489713868 @default.
- W57548255 cites W1524239110 @default.
- W57548255 cites W1531895070 @default.
- W57548255 cites W1536250536 @default.
- W57548255 cites W1545754785 @default.
- W57548255 cites W1547513655 @default.
- W57548255 cites W1553552908 @default.
- W57548255 cites W1576430329 @default.
- W57548255 cites W1578550907 @default.
- W57548255 cites W1587897251 @default.
- W57548255 cites W158863100 @default.
- W57548255 cites W1597146577 @default.
- W57548255 cites W1633118497 @default.
- W57548255 cites W1654040118 @default.
- W57548255 cites W1655247369 @default.
- W57548255 cites W1666860950 @default.
- W57548255 cites W1713895945 @default.
- W57548255 cites W1758644208 @default.
- W57548255 cites W1822640919 @default.
- W57548255 cites W1828538530 @default.
- W57548255 cites W1870692950 @default.
- W57548255 cites W1892978510 @default.
- W57548255 cites W190501440 @default.
- W57548255 cites W1929026110 @default.
- W57548255 cites W1933205484 @default.
- W57548255 cites W1939097681 @default.
- W57548255 cites W1939219220 @default.
- W57548255 cites W1956615634 @default.
- W57548255 cites W195679711 @default.
- W57548255 cites W1963554551 @default.
- W57548255 cites W1964255154 @default.
- W57548255 cites W1964731035 @default.
- W57548255 cites W1964749135 @default.
- W57548255 cites W1965167411 @default.
- W57548255 cites W1965174921 @default.
- W57548255 cites W1965260202 @default.
- W57548255 cites W1965462583 @default.
- W57548255 cites W1965508391 @default.
- W57548255 cites W1966071169 @default.
- W57548255 cites W1966377499 @default.
- W57548255 cites W1967027549 @default.
- W57548255 cites W1967233463 @default.
- W57548255 cites W1967435385 @default.
- W57548255 cites W1967770064 @default.
- W57548255 cites W1968014398 @default.
- W57548255 cites W1968143490 @default.
- W57548255 cites W1968729959 @default.
- W57548255 cites W1968813442 @default.
- W57548255 cites W1968834749 @default.
- W57548255 cites W1969199485 @default.
- W57548255 cites W1969768785 @default.
- W57548255 cites W1970305440 @default.
- W57548255 cites W1971334427 @default.
- W57548255 cites W1971362678 @default.
- W57548255 cites W1971484703 @default.
- W57548255 cites W1972006156 @default.
- W57548255 cites W1973411450 @default.
- W57548255 cites W1974204973 @default.
- W57548255 cites W1974262619 @default.
- W57548255 cites W1974482259 @default.
- W57548255 cites W1974706988 @default.
- W57548255 cites W1976208970 @default.
- W57548255 cites W1977033986 @default.
- W57548255 cites W1977198272 @default.
- W57548255 cites W1977232760 @default.
- W57548255 cites W1977444106 @default.
- W57548255 cites W1977663091 @default.
- W57548255 cites W1977977170 @default.
- W57548255 cites W1978122530 @default.
- W57548255 cites W1978189785 @default.
- W57548255 cites W1979229371 @default.
- W57548255 cites W1979581462 @default.
- W57548255 cites W1979743745 @default.
- W57548255 cites W1979763855 @default.
- W57548255 cites W1979825096 @default.
- W57548255 cites W1980122962 @default.
- W57548255 cites W1980860059 @default.
- W57548255 cites W1981155443 @default.
- W57548255 cites W1982479291 @default.
- W57548255 cites W1982690930 @default.
- W57548255 cites W1983359113 @default.
- W57548255 cites W1984832774 @default.
- W57548255 cites W1985057945 @default.