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- W57707213 abstract "This chapter focuses on the discoveries and developments that laid the foundations for the practical applications of deoxyribonucleic acid (DNA) technology. The chapter begins by discussing that genetic alterations— using DNA technology, permit scientists to manipulate organisms. The technology has been made possible by knowledge of microorganisms, which were researched over the decades. The biochemistry and genetics of the bacterium Escherichia coli are outlined, and the replication patterns of viruses are discussed. The genetic recombinations in a bacteria including: transformation, conjugation, and transduction are also reviewed. The chapter describes the way interest in DNA technology heightened with the discovery of restriction enzymes. Using these enzymes, the biochemists united the DNA fragments from different sources to construct a recombinant DNA molecule. In 1973, Stanley Cohen and Herbert Boyer performed several experiments in gene-splicing that launched the era of DNA technology. Safety concerns erupted later leading to the Asilomar conference, to establish guidelines for conducting experiments in DNA technology. The gene-splicing technology has profound consequences in pure and practical research. Pharmaceutical products, agricultural advances, gene therapy, and the novel approaches to forensic science are some examples." @default.
- W57707213 created "2016-06-24" @default.
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- W57707213 date "2001-01-01" @default.
- W57707213 modified "2023-10-17" @default.
- W57707213 title "Foundations of DNA Technology" @default.
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- W57707213 doi "https://doi.org/10.1016/b978-012048920-6/50004-5" @default.
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