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- W577388959 abstract "The role of fatty acids in mediating inflammatory processes in human skin is clearly established. The mechanisms by which they operate extend from gross physico-chemical changes, e.g. in cell membrane properties, to highly specific, receptor-mediated, cell activation. The population of fatty acid molecules is in a state of flux, free acids being continuously taken up into specific lipid pools and released from these. In addition, they are subject to metabolic and oxidative modifications, both in the free and bound forms, leading to a wide variety of molecular species, several of which have important biological activities. A number of excellent practical texts for use on the laboratory bench exist, in which the methods for fatty acid extraction, purification and analysis are described in detail, including the books by Christie and Hamilton and Hamilton [1,2]. In this review I have taken examples of protocols from a wide range of human matrices, as the methods describe therein apply equally to samples of dermal relevance." @default.
- W577388959 created "2016-06-24" @default.
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- W577388959 date "1999-01-01" @default.
- W577388959 modified "2023-09-23" @default.
- W577388959 title "Strategies for the analysis of fatty acid mediators of inflammation" @default.
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- W577388959 doi "https://doi.org/10.1007/978-3-0348-8761-8_8" @default.
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