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- W577600972 abstract "The medial prefrontal cortex (mPFC) is involved in performance-monitoring andhas been implicated in the generation of several electrocortical responses associated withself-regulation. The error-related negativity (ERN), the inhibitory Nogo N2 (N2), and thefeedback-related negativity (FRN) are event-related potential (ERP) components whichreflect mPFC activity associated with feedback to behavioural (ERN, N2) andenvironmental (FRN) consequences. Our main goal was to determine whether or notrnPFC activation varies as a function of motivational context (e.g., those involvingperformance-related incentives) or the use of internally versus externally generatedfeedback signals (i.e., errors). Additionally, we assessed medial prefrontal activity inrelation to individual differences in personality and temperament.Participants completed a combination of tasks in which performance-related incentives were associated with task performance and feedback generated from internal versus external responses. MPFC activity was indexed using both ERP scalp voltage peaks and intracerebral current source density (CSD) of dorsal and ventral regions. Additionally, participants completed several questionnaires assessing personality and temperament styles.Given previous studies have shown that enhanced mPFC activity to loss (or negative) feedback, we expected that activity in the mPFC would generally be greater during the Loss condition relative to the Win condition for both the ERN and N2. Also,due to the evidence that the (vmPFC) is engaged in arousing contexts, we hypothesizedthat activity in the ventromedial prefrontal cortex (vmPFC) would be greater than activityin the dorsomedial prefrontal cortex (dmPFC), especially in the Loss condition of the GoNogo task (ERN). Similarly, loss feedback in the BART (FRN) was expected to engage the vmPFC more than the dmPFC. Finally, we predicted that persons rating themselves as more willing to engage in approach-related behaviours or to exhibit rigid cognitive styles would show reduced activity of the mPFC.Overall, our results emphasize the role of affective evaluations of behavioural andenvironmental consequences when self-regulating. Although there were no effects ofcontext on brain activity, our data indicate that, during the time of the ERN and N2 on theMW Go-Nogo task and the FRN on the BART, the vrnPFC was more active compared tothe dmPFC. Moreover, regional recruitment in the mPFC was similar across internally(ERN) and externally (FRN) generated errors signals associated with loss feedback, asreflected by relatively greater activity in the vmPFC than the dmPFC.Our data also suggest that greater activity in the mPFC is associated with better inhibitory control, as reflected by both scalp and CSD measures. Additionally, deactivation of the subgenual anterior cingulate cortex (sgACC) and lower levels of self-reported positive affect were both related to increased voluntary risk-taking on the BART. Finally, persons reporting higher levels of…" @default.
- W577600972 created "2016-06-24" @default.
- W577600972 creator A5027720359 @default.
- W577600972 creator A5074063899 @default.
- W577600972 date "2013-04-15" @default.
- W577600972 modified "2023-09-26" @default.
- W577600972 title "Hot cognition and activation of the medial prefrontal cortex: Self-regulating in contexts involving motivational pressures" @default.
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