Matches in SemOpenAlex for { <https://semopenalex.org/work/W577980181> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W577980181 endingPage "972" @default.
- W577980181 startingPage "965" @default.
- W577980181 abstract "The effects of probucol on serum lipids, lipoprotein lipids, serum α-tocopherol and Co-Q10 were studied in 28 patients with type II hyperlipo-proteinemia.The patients received 2×250mg of probucol per day for 16 weeks.Total cholesterol, triglyceride and phospholipid were significantly reduced with probucol (20%, 17%, 18% respectively). LDL and HDL cholesterol were also reduced significantly (14%, 10% respectively), but atherogenic index (VLDL+LDL-Ch/HDL-Ch) was not significantly changed. The extent of the fall in total cholesterol was directly proportional to the pre-treatment total cholesterol level, the higher this level the greater the decrement. HDL-cholesterol fell by 46% in patients whose pre-treatment HDL-cholesterol levels were over 50mg/dl, but did not fall in patients whose pretreatment levels were under 40mg/dl.There was no significant change in serum α-tocopherol-concentration.Serum Coenzyme Q10 concentration were significantly reduced from 1, 765±308μg/ml to 1, 109±153μg/ml. Generally the drug was well accepted and free of significant toxic effects.These results suggested that probucol in a dose of 500mg/day appeared to be useful for the treatment in patients with type II hyperlipoproteinemia." @default.
- W577980181 created "2016-06-24" @default.
- W577980181 creator A5002505123 @default.
- W577980181 creator A5009068793 @default.
- W577980181 creator A5021790885 @default.
- W577980181 creator A5056160614 @default.
- W577980181 creator A5067450689 @default.
- W577980181 creator A5069083646 @default.
- W577980181 creator A5083418367 @default.
- W577980181 date "1984-01-01" @default.
- W577980181 modified "2023-10-17" @default.
- W577980181 title "Effects of Probucol on Serum Lipids, Lipoprotein Lipids, Serum α-Tocopherol and Serum Coenzyme Q<sub>10</sub> in Patients with Type II Hyperlipoproteinemia" @default.
- W577980181 cites W1853301110 @default.
- W577980181 cites W1921017818 @default.
- W577980181 cites W1970485370 @default.
- W577980181 cites W1988000529 @default.
- W577980181 cites W2034803661 @default.
- W577980181 cites W2039821372 @default.
- W577980181 cites W2072092506 @default.
- W577980181 cites W2073378086 @default.
- W577980181 cites W2118710116 @default.
- W577980181 cites W2160599035 @default.
- W577980181 cites W2415081045 @default.
- W577980181 doi "https://doi.org/10.5551/jat1973.12.4_965" @default.
- W577980181 hasPublicationYear "1984" @default.
- W577980181 type Work @default.
- W577980181 sameAs 577980181 @default.
- W577980181 citedByCount "0" @default.
- W577980181 crossrefType "journal-article" @default.
- W577980181 hasAuthorship W577980181A5002505123 @default.
- W577980181 hasAuthorship W577980181A5009068793 @default.
- W577980181 hasAuthorship W577980181A5021790885 @default.
- W577980181 hasAuthorship W577980181A5056160614 @default.
- W577980181 hasAuthorship W577980181A5067450689 @default.
- W577980181 hasAuthorship W577980181A5069083646 @default.
- W577980181 hasAuthorship W577980181A5083418367 @default.
- W577980181 hasBestOaLocation W5779801811 @default.
- W577980181 hasConcept C126322002 @default.
- W577980181 hasConcept C134018914 @default.
- W577980181 hasConcept C139572402 @default.
- W577980181 hasConcept C185592680 @default.
- W577980181 hasConcept C2776167589 @default.
- W577980181 hasConcept C2777551382 @default.
- W577980181 hasConcept C2778004101 @default.
- W577980181 hasConcept C2778163477 @default.
- W577980181 hasConcept C2778913445 @default.
- W577980181 hasConcept C2778918659 @default.
- W577980181 hasConcept C2779384338 @default.
- W577980181 hasConcept C2779924751 @default.
- W577980181 hasConcept C2780072125 @default.
- W577980181 hasConcept C41625074 @default.
- W577980181 hasConcept C55493867 @default.
- W577980181 hasConcept C71924100 @default.
- W577980181 hasConcept C8243546 @default.
- W577980181 hasConceptScore W577980181C126322002 @default.
- W577980181 hasConceptScore W577980181C134018914 @default.
- W577980181 hasConceptScore W577980181C139572402 @default.
- W577980181 hasConceptScore W577980181C185592680 @default.
- W577980181 hasConceptScore W577980181C2776167589 @default.
- W577980181 hasConceptScore W577980181C2777551382 @default.
- W577980181 hasConceptScore W577980181C2778004101 @default.
- W577980181 hasConceptScore W577980181C2778163477 @default.
- W577980181 hasConceptScore W577980181C2778913445 @default.
- W577980181 hasConceptScore W577980181C2778918659 @default.
- W577980181 hasConceptScore W577980181C2779384338 @default.
- W577980181 hasConceptScore W577980181C2779924751 @default.
- W577980181 hasConceptScore W577980181C2780072125 @default.
- W577980181 hasConceptScore W577980181C41625074 @default.
- W577980181 hasConceptScore W577980181C55493867 @default.
- W577980181 hasConceptScore W577980181C71924100 @default.
- W577980181 hasConceptScore W577980181C8243546 @default.
- W577980181 hasIssue "4" @default.
- W577980181 hasLocation W5779801811 @default.
- W577980181 hasOpenAccess W577980181 @default.
- W577980181 hasPrimaryLocation W5779801811 @default.
- W577980181 hasRelatedWork W1976602105 @default.
- W577980181 hasRelatedWork W1996561303 @default.
- W577980181 hasRelatedWork W2004682325 @default.
- W577980181 hasRelatedWork W2029684747 @default.
- W577980181 hasRelatedWork W2035440468 @default.
- W577980181 hasRelatedWork W2052466812 @default.
- W577980181 hasRelatedWork W2059815559 @default.
- W577980181 hasRelatedWork W2074869070 @default.
- W577980181 hasRelatedWork W2094359346 @default.
- W577980181 hasRelatedWork W2338884341 @default.
- W577980181 hasVolume "12" @default.
- W577980181 isParatext "false" @default.
- W577980181 isRetracted "false" @default.
- W577980181 magId "577980181" @default.
- W577980181 workType "article" @default.