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• W57929727 abstract "Back to table of contents Previous article Next article No AccessREM sleep and depression: common neurobiological control mechanismsPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.139.5.565AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractThe author summarizes clinical data showing parallels between REM sleep and depressive phenomena; e.g., patients with endogenous depression show a first REM period that has a shorter than normal latency and a higher density of eye movement. The author discusses evidence for his hypothesis that the following commonalities in neurobiological control systems generate these parallels: 1) brainstem norepinephrine and serotonin systems suppress both REM sleep and depressive phenomena, 2) acetylcholine systems promote both REM and depressive phenomena, and 3) in control of depressive phenomena, as acetylcholine neuronal systems interact and the balance of activity between these two systems, rather than absolute activity levels in either, is the critical factor. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). 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Hodgman1 April 2006 | Psychiatric Services, Vol. 34, No. 6Sleep Studies in Affective Illness: Diagnostic, Therapeutic, and Pathophysiological ImplicationsPsychiatric Annals, Vol. 13, No. 5Functional Indices of Biological DisturbanceBrain Research, Vol. 274, No. 2ELECTROENCEPHALOGRAPHIC SLEEP CHANGES IN PSYCHIATRIC PATIENTS, Vol. 18Psychiatric Clinics of North America, Vol. 6, No. 1 Volume 139Issue 5 May 1982Pages 565-570 Metrics PDF download History Published online 1 April 2006 Published in print 1 May 1982" @default.
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