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- W57933692 abstract "Research Article1 November 1989free access Autoregulation of RNase III operon by mRNA processing. J.C. Bardwell J.C. Bardwell Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. Search for more papers by this author P. Régnier P. Régnier Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. Search for more papers by this author S.M. Chen S.M. Chen Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. Search for more papers by this author Y. Nakamura Y. Nakamura Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. Search for more papers by this author M. Grunberg-Manago M. Grunberg-Manago Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. Search for more papers by this author D.L. Court D.L. Court Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. Search for more papers by this author J.C. Bardwell J.C. Bardwell Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. Search for more papers by this author P. Régnier P. Régnier Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. Search for more papers by this author S.M. Chen S.M. Chen Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. Search for more papers by this author Y. Nakamura Y. Nakamura Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. Search for more papers by this author M. Grunberg-Manago M. Grunberg-Manago Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. Search for more papers by this author D.L. Court D.L. Court Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. Search for more papers by this author Author Information J.C. Bardwell1, P. Régnier1, S.M. Chen1, Y. Nakamura1, M. Grunberg-Manago1 and D.L. Court1 1Laboratory of Chromosome Biology, Frederick Cancer Research Facility, MD 21701. The EMBO Journal (1989)8:3401-3407https://doi.org/10.1002/j.1460-2075.1989.tb08504.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info RNase III has been implicated in the control of gene expression by the processing of mRNA. We have found that the rnc operon is autoregulated; rnc- mutant strains oversynthesize the operon's mRNA and protein products. A site in the 5′-noncoding region of the operon's message is cleaved by RNase III. This site-specific cleavage appears to be the initial step in the functional inactivation of the message, since the half-life of the cut message is dramatically shorter than that of the uncut message. Previous ArticleNext Article Volume 8Issue 111 November 1989In this issue RelatedDetailsLoading ..." @default.
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- W57933692 title "Autoregulation of RNase III operon by mRNA processing." @default.
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