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- W580931420 abstract "Neonatal Group B Streptococcus (GBS) infection can be life threatening. Recognizing this as an important preventable disease, the CDC issued specific guidelines in 1996. Compelling evidence for a strong protective effect of the screening-based strategy relative to the risk-based strategy led to new recommendations in 2002 for universal screening by vaginal-rectal culture. However, in Louisiana, there is no uniform strategy for GBS control. This study was therefore undertaken as a pilot study for needs assessment to formulate public health policy. The initial phase of this project involved the development of a comprehensive questionnaire. The second phase involved administration of this survey instrument to consenting OB/GYN clinics. The final phase involved statistical analysis using SPSS. Although almost all clinics did universal screening of pregnant women, only 70.6% used laboratory-based screening. Despite recommendations against routine prophylaxis for low-risk deliveries, 57% of planned C sections involved prophylaxis. Only 51.5% of respondents provided prophylaxis for women with prior infants with GBS disease. As recommended, most clinics performed culture-based screening at 35—37 weeks (91.2%), undertook both vaginal and rectal cultures (70.6%), and cultured the lower vagina (69.7%) instead of the cervix (23.3%). In the risk-based approach, clinics used recommended high-risk determinants as follows: gestation below 37 weeks (92.3%) membrane rupture over 18 hours (76.9%); temperature over 100.4 ◦F (73.1%). If culture screening result is unknown at labor, chemoprophylaxis should be based on risk. Only 25% complied with this recommendation. Only 64.3% of respondents treated infection and gave prophylaxis during labor if GBS is isolated from maternal urine. When overall compliance was stratified using the number of recommendations met out of a total of thirteen, 16.7% of institutions showed high compliance, 52.8% medium, and 30.6% low. This study demonstrates that GBS control is less than optimal in Louisiana and necessitates uniform statewide policy to address this need." @default.
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- W580931420 date "2003-09-15" @default.
- W580931420 modified "2023-09-27" @default.
- W580931420 title "Serotypes and Penicillin Susceptibility of Streptococcus pneumoniae Isolated from Clinical Specimens and Healthy Carriers of Korean Children" @default.
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