Matches in SemOpenAlex for { <https://semopenalex.org/work/W584534009> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W584534009 abstract "This thesis reports a number of novel receptors found to facilitate the transmembrane transport of anions in synthetic vesicle systems. A series of structurally simple thioureas were found to function as efficient Cl-/NO3- and Cl-/HCO3- antiporters while the corresponding ureas were inactive. Of these receptors, a simple indolylthiourea was found to be an extremely potent transporter which could function at concentrations as low as 1:25 000 (molar ratio with respect to lipid). Subsequently, a series of bipodal bis-alkyl-indolylureas were found to mediate Cl-/NO3 - antiport, with the observed anion transport found to be highly dependent on the length of the central alkyl chain bridging the two indolylurea moieties. The mechanism of transport and the structure-activity relationships were extensively investigated using a wide range of vesicle-based techniques. The solution phase anion binding properties of these receptors was found to be complex as a result of the flexibility of the receptors and the distance between the binding sites. The binding of dihydrogen phosphate and oxalate by receptors in this series was also demonstrated in the solid state. A series of bipodal bis-phenylthioureas were also found to mediate Cl-/NO3 - and Cl-/HCO3- antiport which was again found to be dependent on the alkyl chain length. The effect of substituent variation on transport activity was also examined, while the solution phase binding properties were found to be similarly complex to the bis-indolylurea receptors. The anion transport activity of a series of strapped calix[4]pyrroles provided by J. L. Sessler and C.-H. Lee was investigated. It was found that the straps were able to encourage transport mechanisms not exhibited by the parent macrocycle, while a series of control compounds were inactive" @default.
- W584534009 created "2016-06-24" @default.
- W584534009 creator A5023057810 @default.
- W584534009 date "2011-08-31" @default.
- W584534009 modified "2023-09-27" @default.
- W584534009 title "The design of synthetic transmembrane carriers for anions" @default.
- W584534009 hasPublicationYear "2011" @default.
- W584534009 type Work @default.
- W584534009 sameAs 584534009 @default.
- W584534009 citedByCount "0" @default.
- W584534009 crossrefType "dissertation" @default.
- W584534009 hasAuthorship W584534009A5023057810 @default.
- W584534009 hasConcept C130316041 @default.
- W584534009 hasConcept C170493617 @default.
- W584534009 hasConcept C178790620 @default.
- W584534009 hasConcept C185592680 @default.
- W584534009 hasConcept C2778689049 @default.
- W584534009 hasConcept C2780263894 @default.
- W584534009 hasConcept C2910532024 @default.
- W584534009 hasConcept C41625074 @default.
- W584534009 hasConcept C55493867 @default.
- W584534009 hasConcept C57181701 @default.
- W584534009 hasConcept C71240020 @default.
- W584534009 hasConcept C8010536 @default.
- W584534009 hasConceptScore W584534009C130316041 @default.
- W584534009 hasConceptScore W584534009C170493617 @default.
- W584534009 hasConceptScore W584534009C178790620 @default.
- W584534009 hasConceptScore W584534009C185592680 @default.
- W584534009 hasConceptScore W584534009C2778689049 @default.
- W584534009 hasConceptScore W584534009C2780263894 @default.
- W584534009 hasConceptScore W584534009C2910532024 @default.
- W584534009 hasConceptScore W584534009C41625074 @default.
- W584534009 hasConceptScore W584534009C55493867 @default.
- W584534009 hasConceptScore W584534009C57181701 @default.
- W584534009 hasConceptScore W584534009C71240020 @default.
- W584534009 hasConceptScore W584534009C8010536 @default.
- W584534009 hasLocation W5845340091 @default.
- W584534009 hasOpenAccess W584534009 @default.
- W584534009 hasPrimaryLocation W5845340091 @default.
- W584534009 hasRelatedWork W2013163713 @default.
- W584534009 hasRelatedWork W2023053168 @default.
- W584534009 hasRelatedWork W2034157360 @default.
- W584534009 hasRelatedWork W2054668319 @default.
- W584534009 hasRelatedWork W2071531304 @default.
- W584534009 hasRelatedWork W2071789184 @default.
- W584534009 hasRelatedWork W2090614925 @default.
- W584534009 hasRelatedWork W2095293401 @default.
- W584534009 hasRelatedWork W2155900654 @default.
- W584534009 hasRelatedWork W2191035281 @default.
- W584534009 hasRelatedWork W2279826563 @default.
- W584534009 hasRelatedWork W2397728578 @default.
- W584534009 hasRelatedWork W2474243213 @default.
- W584534009 hasRelatedWork W2746068041 @default.
- W584534009 hasRelatedWork W2914332664 @default.
- W584534009 hasRelatedWork W2950782836 @default.
- W584534009 hasRelatedWork W2982365748 @default.
- W584534009 hasRelatedWork W2997297442 @default.
- W584534009 hasRelatedWork W3203667345 @default.
- W584534009 hasRelatedWork W807880318 @default.
- W584534009 isParatext "false" @default.
- W584534009 isRetracted "false" @default.
- W584534009 magId "584534009" @default.
- W584534009 workType "dissertation" @default.