Matches in SemOpenAlex for { <https://semopenalex.org/work/W58508590> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W58508590 abstract "P-type ATPases are ubiquitous in all domains of life. Chan, et al. (2010) analyzed P-type ATPases in all the major prokaryotic phyla for which complete genome sequence data were available. The P-type ATPase superfamily consists of thirty-two recognized families, 17 of which are strictly found in prokaryotes. The first seven of these are Families 1-7, which are generally well characterized. Ten functionally uncharacterized P-type ATPase (FUPA) families were identified in as well, FUPA23 through FUPA32. Here, these families are analyzed individually rather than by phyla using the genomic context program SEED (Overbeek et al., 2005) and the co-regulation prediction program RegPredict (Novichkov PS, et al., 2010). By examining the known function of genes co-localized near those encoding FUPAs and using co-localization as a proxy for co- regulation, and finding other genes regulated by similar regulatory sequences, we are able to make highly robust predictions about the putative functions of these ATPases and functionally characterize them. In the process of doing this, unique characteristics of the proteins are illuminated and discussed in the context of phylogeny, environmental context and horizontal gene transfer and how each contributes to the functionality of these ATPases in genomes in which they are found" @default.
- W58508590 created "2016-06-24" @default.
- W58508590 creator A5029357873 @default.
- W58508590 creator A5033506822 @default.
- W58508590 date "2012-01-01" @default.
- W58508590 modified "2023-09-27" @default.
- W58508590 title "Bioinformatic Functional Characterization of the Prokaryotic FUPAs through Co-localization and Co-regulatory Analysis: Taking the FU out of the FUPAs" @default.
- W58508590 hasPublicationYear "2012" @default.
- W58508590 type Work @default.
- W58508590 sameAs 58508590 @default.
- W58508590 citedByCount "0" @default.
- W58508590 crossrefType "journal-article" @default.
- W58508590 hasAuthorship W58508590A5029357873 @default.
- W58508590 hasAuthorship W58508590A5033506822 @default.
- W58508590 hasConcept C104317684 @default.
- W58508590 hasConcept C14036430 @default.
- W58508590 hasConcept C141231307 @default.
- W58508590 hasConcept C151730666 @default.
- W58508590 hasConcept C181199279 @default.
- W58508590 hasConcept C23265538 @default.
- W58508590 hasConcept C2779343474 @default.
- W58508590 hasConcept C54355233 @default.
- W58508590 hasConcept C55493867 @default.
- W58508590 hasConcept C70721500 @default.
- W58508590 hasConcept C78458016 @default.
- W58508590 hasConcept C86803240 @default.
- W58508590 hasConcept C90132467 @default.
- W58508590 hasConcept C91066513 @default.
- W58508590 hasConcept C92938381 @default.
- W58508590 hasConceptScore W58508590C104317684 @default.
- W58508590 hasConceptScore W58508590C14036430 @default.
- W58508590 hasConceptScore W58508590C141231307 @default.
- W58508590 hasConceptScore W58508590C151730666 @default.
- W58508590 hasConceptScore W58508590C181199279 @default.
- W58508590 hasConceptScore W58508590C23265538 @default.
- W58508590 hasConceptScore W58508590C2779343474 @default.
- W58508590 hasConceptScore W58508590C54355233 @default.
- W58508590 hasConceptScore W58508590C55493867 @default.
- W58508590 hasConceptScore W58508590C70721500 @default.
- W58508590 hasConceptScore W58508590C78458016 @default.
- W58508590 hasConceptScore W58508590C86803240 @default.
- W58508590 hasConceptScore W58508590C90132467 @default.
- W58508590 hasConceptScore W58508590C91066513 @default.
- W58508590 hasConceptScore W58508590C92938381 @default.
- W58508590 hasLocation W585085901 @default.
- W58508590 hasOpenAccess W58508590 @default.
- W58508590 hasPrimaryLocation W585085901 @default.
- W58508590 hasRelatedWork W1965642642 @default.
- W58508590 hasRelatedWork W1979716840 @default.
- W58508590 hasRelatedWork W2008152228 @default.
- W58508590 hasRelatedWork W2020156095 @default.
- W58508590 hasRelatedWork W2028193791 @default.
- W58508590 hasRelatedWork W2047618789 @default.
- W58508590 hasRelatedWork W2066797332 @default.
- W58508590 hasRelatedWork W2084214748 @default.
- W58508590 hasRelatedWork W2086194959 @default.
- W58508590 hasRelatedWork W2095624327 @default.
- W58508590 hasRelatedWork W2099770698 @default.
- W58508590 hasRelatedWork W211089543 @default.
- W58508590 hasRelatedWork W2112792893 @default.
- W58508590 hasRelatedWork W2131257296 @default.
- W58508590 hasRelatedWork W2143907955 @default.
- W58508590 hasRelatedWork W2145876138 @default.
- W58508590 hasRelatedWork W2416199421 @default.
- W58508590 hasRelatedWork W2916488234 @default.
- W58508590 hasRelatedWork W2995393338 @default.
- W58508590 hasRelatedWork W85888049 @default.
- W58508590 isParatext "false" @default.
- W58508590 isRetracted "false" @default.
- W58508590 magId "58508590" @default.
- W58508590 workType "article" @default.