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- W58799223 abstract "Transitional cell carcinoma of the urothelium is a chemosensitive malignancy. It is well established that combination chemotherapy routinely alters the natural history of both locally unresectable and metastatic disease. Unfortunately, substantial clinical advances in the treatment of urothelial cancer with cytotoxics have not been apparent since the advent of combination therapy a generation ago. Despite high response rates, and the appearance of second, third, and even fourth-line regimens that produce objective responses, the median survival of patients with metastatic urothelial cancer has consistently been reported in the range of 12–14 mo. Even though this is more than double the expectation of survival with no therapy, and a reliable, palliative benefit is beyond question, systemic therapy with cytotoxic agents is nonetheless stranded on a very modest plateau (1)." @default.
- W58799223 created "2016-06-24" @default.
- W58799223 creator A5027897588 @default.
- W58799223 creator A5034988446 @default.
- W58799223 date "2001-01-01" @default.
- W58799223 modified "2023-09-23" @default.
- W58799223 title "New Possibilities in Systemic Treatment for Metastatic Bladder Cancer" @default.
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