Matches in SemOpenAlex for { <https://semopenalex.org/work/W591915077> ?p ?o ?g. }
- W591915077 abstract "BACKGROUND: Amino acids are essential for protein synthesis and muscle formation and are involved in numerous metabolic pathways affecting exercise metabolism. Consequently, it has been suggested that athletes involved in intense training and competition, supplement their diet with specific amino acids. For example, oral supplementation with glycine-arginine-alpha-ketoisocaproic acid (GAKIC) has previously been shown to improve performance during exhaustive high-intensity anaerobic isokinetic exercise [1] and attenuate the decline in mean power during five repeated cycle sprints [2]. PURPOSE: The aim of the present study is to examine the effects of GAKIC on fatigue during prolonged, repeated cycle sprints in trained cyclists. METHODS: After at least two familiarisation trials, seven well-trained male cyclists (Aged 25-44 years) completed two supramaximal sprint tests each involving 10 sprints of 10 s separated by 50 s rest intervals on an electrically braked cycle ergometer. Computer software was used to calculate power output at each second of the sprint allowing calculation of both 10 second mean power and peak power output. Furthermore, the fatigue index was determined using the following equation: fatigue index % = [(peak power – minimum power)/peak power] x 100. During a period of 45 min prior to these two tests, subjects ingested 11.2 g of GAKIC (2.0 g glycine plus 6.0 g L-arginine monohydrochloride plus 3.2 g [alpha]-ketoisocaproic acid calcium salt) or placebo (Pl) (composed of 9.46 g sucrose plus 3.2 g calcium carbonate) administered in a randomised and double blind fashion. Supplements were dissolved in 450 ml of sugar free fruit juice, divided into 3 equal aliquots of 150ml and consumed 45, 30 and 20 min prior to the trial. RESULTS: Peak power declined from the 1st sprint (mean s.d.) (Pl: 1332 307, GAKIC: 1367 342 W) to the 10th sprint (Pl: 1091 229, GAKIC: 1061 272 W) but did not differ between treatments (P=0.88). Mean power declined from the 1st sprint (Pl: 892 151, GAKIC: 892 153 W) to the 10th sprint (Pl: 766 120, GAKIC: 752 138 W) but did not differ between treatments (P=0.96). In general, the fatigue index remained stable throughout the series of sprints and did not differ between treatments (P=0.99). Subject’s rating of perceived exertion increased from the 1st sprint (Pl: 13 3, GAKIC: 13 3) to the 10th sprint (Pl: 19 1, GAKIC: 20 1) but did not differ between treatments (P=0.11). CONCLUSIONS: In contrast to previous studies, these results do not support an ergogenic effect of GAKIC during repeated bouts of high intensity exercise. REFERENCES: 1. Stevens BR, Godfrey MD, Kaminski TW & Braith RW (2000). High-intensity dynamic human performance enhanced by a metabolic intervention. Med Sci Sports Exerc, 32: 2102-2108.2. Buford BN & Kock AJ (2004). Glycine-Arginine-[alpha]-ketoisocaproic acid improves performance of repeated cycling sprints. Med Sci Sports Exerc, 36: 583-587." @default.
- W591915077 created "2016-06-24" @default.
- W591915077 creator A5001484592 @default.
- W591915077 creator A5009104211 @default.
- W591915077 creator A5023036442 @default.
- W591915077 creator A5036343453 @default.
- W591915077 creator A5045734974 @default.
- W591915077 creator A5063566363 @default.
- W591915077 creator A5064112326 @default.
- W591915077 creator A5074113993 @default.
- W591915077 creator A5090826557 @default.
- W591915077 creator A5091774283 @default.
- W591915077 date "2008-07-01" @default.
- W591915077 modified "2023-09-27" @default.
- W591915077 title "Glycine-arginine-alpha-ketoisocaproic acid does not improve performance of repeated supramaximal cycling sprints in trained cyclists" @default.
- W591915077 cites W2047313075 @default.
- W591915077 cites W2138516497 @default.
- W591915077 hasPublicationYear "2008" @default.
- W591915077 type Work @default.
- W591915077 sameAs 591915077 @default.
- W591915077 citedByCount "0" @default.
- W591915077 crossrefType "journal-article" @default.
- W591915077 hasAuthorship W591915077A5001484592 @default.
- W591915077 hasAuthorship W591915077A5009104211 @default.
- W591915077 hasAuthorship W591915077A5023036442 @default.
- W591915077 hasAuthorship W591915077A5036343453 @default.
- W591915077 hasAuthorship W591915077A5045734974 @default.
- W591915077 hasAuthorship W591915077A5063566363 @default.
- W591915077 hasAuthorship W591915077A5064112326 @default.
- W591915077 hasAuthorship W591915077A5074113993 @default.
- W591915077 hasAuthorship W591915077A5090826557 @default.
- W591915077 hasAuthorship W591915077A5091774283 @default.
- W591915077 hasConcept C126322002 @default.
- W591915077 hasConcept C134018914 @default.
- W591915077 hasConcept C140793950 @default.
- W591915077 hasConcept C142724271 @default.
- W591915077 hasConcept C166957645 @default.
- W591915077 hasConcept C185592680 @default.
- W591915077 hasConcept C1862650 @default.
- W591915077 hasConcept C204787440 @default.
- W591915077 hasConcept C27081682 @default.
- W591915077 hasConcept C2776868573 @default.
- W591915077 hasConcept C2777468819 @default.
- W591915077 hasConcept C2777953023 @default.
- W591915077 hasConcept C2779701627 @default.
- W591915077 hasConcept C2994262451 @default.
- W591915077 hasConcept C5140985 @default.
- W591915077 hasConcept C515207424 @default.
- W591915077 hasConcept C541528975 @default.
- W591915077 hasConcept C55493867 @default.
- W591915077 hasConcept C71924100 @default.
- W591915077 hasConcept C84393581 @default.
- W591915077 hasConcept C86803240 @default.
- W591915077 hasConcept C95457728 @default.
- W591915077 hasConceptScore W591915077C126322002 @default.
- W591915077 hasConceptScore W591915077C134018914 @default.
- W591915077 hasConceptScore W591915077C140793950 @default.
- W591915077 hasConceptScore W591915077C142724271 @default.
- W591915077 hasConceptScore W591915077C166957645 @default.
- W591915077 hasConceptScore W591915077C185592680 @default.
- W591915077 hasConceptScore W591915077C1862650 @default.
- W591915077 hasConceptScore W591915077C204787440 @default.
- W591915077 hasConceptScore W591915077C27081682 @default.
- W591915077 hasConceptScore W591915077C2776868573 @default.
- W591915077 hasConceptScore W591915077C2777468819 @default.
- W591915077 hasConceptScore W591915077C2777953023 @default.
- W591915077 hasConceptScore W591915077C2779701627 @default.
- W591915077 hasConceptScore W591915077C2994262451 @default.
- W591915077 hasConceptScore W591915077C5140985 @default.
- W591915077 hasConceptScore W591915077C515207424 @default.
- W591915077 hasConceptScore W591915077C541528975 @default.
- W591915077 hasConceptScore W591915077C55493867 @default.
- W591915077 hasConceptScore W591915077C71924100 @default.
- W591915077 hasConceptScore W591915077C84393581 @default.
- W591915077 hasConceptScore W591915077C86803240 @default.
- W591915077 hasConceptScore W591915077C95457728 @default.
- W591915077 hasLocation W5919150771 @default.
- W591915077 hasOpenAccess W591915077 @default.
- W591915077 hasPrimaryLocation W5919150771 @default.
- W591915077 hasRelatedWork W1493137865 @default.
- W591915077 hasRelatedWork W2111568296 @default.
- W591915077 hasRelatedWork W2138516497 @default.
- W591915077 hasRelatedWork W2146662443 @default.
- W591915077 hasRelatedWork W2149117208 @default.
- W591915077 hasRelatedWork W2164110698 @default.
- W591915077 hasRelatedWork W2474659002 @default.
- W591915077 hasRelatedWork W2609801401 @default.
- W591915077 hasRelatedWork W2802277815 @default.
- W591915077 hasRelatedWork W2968338905 @default.
- W591915077 hasRelatedWork W3000254596 @default.
- W591915077 hasRelatedWork W3030542893 @default.
- W591915077 hasRelatedWork W3151283304 @default.
- W591915077 hasRelatedWork W3165230037 @default.
- W591915077 hasRelatedWork W51677617 @default.
- W591915077 hasRelatedWork W581655815 @default.
- W591915077 hasRelatedWork W88230114 @default.
- W591915077 hasRelatedWork W2108733903 @default.
- W591915077 hasRelatedWork W2463955767 @default.
- W591915077 hasRelatedWork W2683435319 @default.
- W591915077 isParatext "false" @default.