FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W5921850> ?p ?o ?g. }

• W5921850 abstract "The ascending 5-hydroxytryptamine (5-HT, serotonin) containing neurons first described by Fuxe et al.1, which originate in the midbrain raphe nuclei and have a widespread distribution in the forebrain2,3 have been implicated in avoidance learning and memory processes 4,5,6,7,8,9. Treatments known to modulate 5-HT neurotransmission have been found to alter the acquisition and performance of a wide range of aversively motivated behaviors10,11. Despite intensive research, however, the specific role of serotonin in aversive learning and memory processes is little understood. In recent years it has become increasingly clear that different methods used to manipulate 5-HT neurotransmission can produce highly variable effects on avoidance behavior in the rat even when the animals are tested in similar behavioral situations11,12,13. The available data suggest that the variations in avoidance behavior following 5-HT manipulation depend on both the tools employed to alter 5-HT neurotransmission and the behavioral situation used for testing the animals11. The same manipulation of central 5-HT has been shown to cause different effects on avoidance learning when the testing situation is varied. For example, systemic injection of pchlorophenylalanine (PCPA), a tryptophan hydroxylase inhibitor, has been reported to facilitate one-way avoidance acquisition6,7, but was recently shown not to significantly affect two-way active avoidance acquisition 12. On the other hand, electrolytic lesions of the midbrain raphe nuclei, which produce a marked reduction in forebrain 5-HT concentrations, but in contrast to PCPA do not affect peripheral 5-HT stores, have consistently been shown to facilitate two-way and to impair one-way avoidance acquisition 11,14. Thus, reduction of brain 5-HT concentrations can produce highly variable effects on avoidance learning." @default.
• W5921850 created "2016-06-24" @default.
• W5921850 creator A5035523228 @default.
• W5921850 creator A5038000864 @default.
• W5921850 creator A5048178648 @default.
• W5921850 creator A5048458525 @default.
• W5921850 creator A5067222102 @default.
• W5921850 creator A5091629113 @default.
• W5921850 date "1981-01-01" @default.
• W5921850 modified "2023-10-15" @default.
• W5921850 title "Studies on the Role of Central 5-HT Neurons in Avoidance Learning: A Behavioral and Biochemical Analysis" @default.
• W5921850 cites W1970590469 @default.
• W5921850 cites W1980840359 @default.
• W5921850 cites W1981462317 @default.
• W5921850 cites W1987193120 @default.
• W5921850 cites W1989901803 @default.
• W5921850 cites W1990106556 @default.
• W5921850 cites W1992463071 @default.
• W5921850 cites W1995544598 @default.
• W5921850 cites W1999286993 @default.
• W5921850 cites W2002850009 @default.
• W5921850 cites W2004949823 @default.
• W5921850 cites W2004969635 @default.
• W5921850 cites W2005329999 @default.
• W5921850 cites W2015768769 @default.
• W5921850 cites W2049034169 @default.
• W5921850 cites W2049363721 @default.
• W5921850 cites W2050611549 @default.
• W5921850 cites W2051573571 @default.
• W5921850 cites W2055273921 @default.
• W5921850 cites W2062132794 @default.
• W5921850 cites W2069618603 @default.
• W5921850 cites W2075634000 @default.
• W5921850 cites W2081188214 @default.
• W5921850 cites W2083889277 @default.
• W5921850 cites W2094526136 @default.
• W5921850 cites W2160824435 @default.
• W5921850 cites W4253080718 @default.
• W5921850 doi "https://doi.org/10.1007/978-1-4684-3860-4_37" @default.
• W5921850 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6459009" @default.
• W5921850 hasPublicationYear "1981" @default.
• W5921850 type Work @default.
• W5921850 sameAs 5921850 @default.
• W5921850 citedByCount "38" @default.
• W5921850 crossrefType "book-chapter" @default.
• W5921850 hasAuthorship W5921850A5035523228 @default.
• W5921850 hasAuthorship W5921850A5038000864 @default.
• W5921850 hasAuthorship W5921850A5048178648 @default.
• W5921850 hasAuthorship W5921850A5048458525 @default.
• W5921850 hasAuthorship W5921850A5067222102 @default.
• W5921850 hasAuthorship W5921850A5091629113 @default.
• W5921850 hasConcept C126322002 @default.
• W5921850 hasConcept C146926590 @default.
• W5921850 hasConcept C15744967 @default.
• W5921850 hasConcept C169760540 @default.
• W5921850 hasConcept C170493617 @default.
• W5921850 hasConcept C200170125 @default.
• W5921850 hasConcept C2775864247 @default.
• W5921850 hasConcept C2777615928 @default.
• W5921850 hasConcept C2777865548 @default.
• W5921850 hasConcept C2779715522 @default.
• W5921850 hasConcept C37000724 @default.
• W5921850 hasConcept C529278444 @default.
• W5921850 hasConcept C53910766 @default.
• W5921850 hasConcept C552161191 @default.
• W5921850 hasConcept C71924100 @default.
• W5921850 hasConceptScore W5921850C126322002 @default.
• W5921850 hasConceptScore W5921850C146926590 @default.
• W5921850 hasConceptScore W5921850C15744967 @default.
• W5921850 hasConceptScore W5921850C169760540 @default.
• W5921850 hasConceptScore W5921850C170493617 @default.
• W5921850 hasConceptScore W5921850C200170125 @default.
• W5921850 hasConceptScore W5921850C2775864247 @default.
• W5921850 hasConceptScore W5921850C2777615928 @default.
• W5921850 hasConceptScore W5921850C2777865548 @default.
• W5921850 hasConceptScore W5921850C2779715522 @default.
• W5921850 hasConceptScore W5921850C37000724 @default.
• W5921850 hasConceptScore W5921850C529278444 @default.
• W5921850 hasConceptScore W5921850C53910766 @default.
• W5921850 hasConceptScore W5921850C552161191 @default.
• W5921850 hasConceptScore W5921850C71924100 @default.
• W5921850 hasLocation W59218501 @default.
• W5921850 hasLocation W59218502 @default.
• W5921850 hasOpenAccess W5921850 @default.
• W5921850 hasPrimaryLocation W59218501 @default.
• W5921850 hasRelatedWork W1555510654 @default.
• W5921850 hasRelatedWork W195303848 @default.
• W5921850 hasRelatedWork W1978632621 @default.
• W5921850 hasRelatedWork W1987096130 @default.
• W5921850 hasRelatedWork W2062436102 @default.
• W5921850 hasRelatedWork W2109886903 @default.
• W5921850 hasRelatedWork W2113403150 @default.
• W5921850 hasRelatedWork W2139624959 @default.
• W5921850 hasRelatedWork W2547264006 @default.
• W5921850 hasRelatedWork W998192002 @default.
• W5921850 isParatext "false" @default.
• W5921850 isRetracted "false" @default.
• W5921850 magId "5921850" @default.
• W5921850 workType "book-chapter" @default.