FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W593364932> ?p ?o ?g. }

• W593364932 abstract "Analyzing the stability of SCF ubiquitin ligases is worth investigating because these complexes are involved in many cellular processes including cell cycle regulation, DNA repair mechanisms, and gene expression. On the other hand, interactions of two (or more) proteins are controlled by their domains – compact functional units of proteins. As a consequence, in this study, we have analyzed the role of Pfam domain interactions in predicting the stability of protein-protein interactions (PPIs) that are known or predicted to occur involving subunit components of the SCF ligase complex. Moreover, employing the most relevant and discriminating features is very important to achieve a successful prediction with low computational cost. Although, different feature selection methods have been recently developed for this purpose, feature grouping is a better idea, especially when dealing with high-dimensional sparse feature vectors, yielding better interpretation of the data. In this paper, a correlation-based feature grouping (CFG) method is proposed to group and combine the features. To demonstrate the strength of CFG, two filter methods of χ 2 and correlation are also employed for feature selection and prediction is performed using different methods including a support vector machine (SVM) and k-Nearest Neighbor (k-NN). The experimental results on a dataset of SCF ligases indicate that employing feature grouping achieves significant increases of 10% for svm and 13% for k-NN, being more efficient than employing feature selection in identifying a set of relevant features" @default.
• W593364932 created "2016-06-24" @default.
• W593364932 creator A5009621896 @default.
• W593364932 creator A5027262289 @default.
• W593364932 creator A5040978295 @default.
• W593364932 date "2015-01-01" @default.
• W593364932 modified "2023-09-27" @default.
• W593364932 title "A Computational Domain-Based Feature Grouping Approach for Prediction of Stability of SCF Ligases" @default.
• W593364932 cites W1975505516 @default.
• W593364932 cites W1975888060 @default.
• W593364932 cites W1983597257 @default.
• W593364932 cites W1984694072 @default.
• W593364932 cites W1986627655 @default.
• W593364932 cites W1995515386 @default.
• W593364932 cites W2012653948 @default.
• W593364932 cites W2021875518 @default.
• W593364932 cites W2028435699 @default.
• W593364932 cites W2031772330 @default.
• W593364932 cites W2053502852 @default.
• W593364932 cites W2058473162 @default.
• W593364932 cites W2063672599 @default.
• W593364932 cites W2065825739 @default.
• W593364932 cites W2082074261 @default.
• W593364932 cites W2116063398 @default.
• W593364932 cites W2119862467 @default.
• W593364932 cites W2131298020 @default.
• W593364932 cites W2133990480 @default.
• W593364932 cites W2141826465 @default.
• W593364932 cites W2141885858 @default.
• W593364932 cites W2332240239 @default.
• W593364932 cites W4248974836 @default.
• W593364932 doi "https://doi.org/10.1007/978-3-319-16483-0_61" @default.
• W593364932 hasPublicationYear "2015" @default.
• W593364932 type Work @default.
• W593364932 sameAs 593364932 @default.
• W593364932 citedByCount "1" @default.
• W593364932 countsByYear W5933649322015 @default.
• W593364932 crossrefType "book-chapter" @default.
• W593364932 hasAuthorship W593364932A5009621896 @default.
• W593364932 hasAuthorship W593364932A5027262289 @default.
• W593364932 hasAuthorship W593364932A5040978295 @default.
• W593364932 hasConcept C106131492 @default.
• W593364932 hasConcept C112972136 @default.
• W593364932 hasConcept C113238511 @default.
• W593364932 hasConcept C119857082 @default.
• W593364932 hasConcept C12267149 @default.
• W593364932 hasConcept C124101348 @default.
• W593364932 hasConcept C134306372 @default.
• W593364932 hasConcept C138885662 @default.
• W593364932 hasConcept C148483581 @default.
• W593364932 hasConcept C153180895 @default.
• W593364932 hasConcept C154945302 @default.
• W593364932 hasConcept C2776401178 @default.
• W593364932 hasConcept C31972630 @default.
• W593364932 hasConcept C33923547 @default.
• W593364932 hasConcept C36503486 @default.
• W593364932 hasConcept C41008148 @default.
• W593364932 hasConcept C41895202 @default.
• W593364932 hasConcept C83665646 @default.
• W593364932 hasConceptScore W593364932C106131492 @default.
• W593364932 hasConceptScore W593364932C112972136 @default.
• W593364932 hasConceptScore W593364932C113238511 @default.
• W593364932 hasConceptScore W593364932C119857082 @default.
• W593364932 hasConceptScore W593364932C12267149 @default.
• W593364932 hasConceptScore W593364932C124101348 @default.
• W593364932 hasConceptScore W593364932C134306372 @default.
• W593364932 hasConceptScore W593364932C138885662 @default.
• W593364932 hasConceptScore W593364932C148483581 @default.
• W593364932 hasConceptScore W593364932C153180895 @default.
• W593364932 hasConceptScore W593364932C154945302 @default.
• W593364932 hasConceptScore W593364932C2776401178 @default.
• W593364932 hasConceptScore W593364932C31972630 @default.
• W593364932 hasConceptScore W593364932C33923547 @default.
• W593364932 hasConceptScore W593364932C36503486 @default.
• W593364932 hasConceptScore W593364932C41008148 @default.
• W593364932 hasConceptScore W593364932C41895202 @default.
• W593364932 hasConceptScore W593364932C83665646 @default.
• W593364932 hasLocation W5933649321 @default.
• W593364932 hasOpenAccess W593364932 @default.
• W593364932 hasPrimaryLocation W5933649321 @default.
• W593364932 hasRelatedWork W1980690213 @default.
• W593364932 hasRelatedWork W1983597257 @default.
• W593364932 hasRelatedWork W1991576509 @default.
• W593364932 hasRelatedWork W2009902967 @default.
• W593364932 hasRelatedWork W2020314029 @default.
• W593364932 hasRelatedWork W2041185135 @default.
• W593364932 hasRelatedWork W2070436225 @default.
• W593364932 hasRelatedWork W2078999665 @default.
• W593364932 hasRelatedWork W2087322782 @default.
• W593364932 hasRelatedWork W2098468136 @default.
• W593364932 hasRelatedWork W2135483587 @default.
• W593364932 hasRelatedWork W2142355963 @default.
• W593364932 hasRelatedWork W2240764086 @default.
• W593364932 hasRelatedWork W2404698030 @default.
• W593364932 hasRelatedWork W2412867351 @default.
• W593364932 hasRelatedWork W2776283197 @default.
• W593364932 hasRelatedWork W2891807655 @default.
• W593364932 hasRelatedWork W2901966228 @default.
• W593364932 hasRelatedWork W32612843 @default.
• W593364932 hasRelatedWork W56583085 @default.

• next