FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W59372955> ?p ?o ?g. }

• W59372955 endingPage "108" @default.
• W59372955 startingPage "97" @default.
• W59372955 abstract "Most neurodegenerative disorders are insidious with substantial neural injury present well before symptoms are revealed. Thus, at the time of evident disability or impairment, secondary injuries may obscure the inciting neuropathology. This is not true of stroke, where the onset of injury and symptomatology typically coincide. Moreover, there is a distinct and relatively brief temporal pattern of injury. Therefore, models of ischemia/reperfusion can provide significant insight into early and late injuries and the specific mechanisms of each component of injury. Modelling hypoxia and reoxygenation in primary cultures of hippocampal and cortical neurons to examine temporally the source of reactive oxygen species has identified three phases of reactive oxygen species production in hypoxia/reoxygenation. Mitochondria respond first but are quickly limited by the insufficient oxygen. At this point in ischemia, xanthine oxidase becomes an important source of superoxide, whereas during reperfusion NADPH oxidase is a major source of superoxide. This work highlights the value of a model of early and temporally distinct phases of injury and supports the concept that multitarget approaches will be necessary to effectively prevent or reduce neural injury of stroke." @default.
• W59372955 created "2016-06-24" @default.
• W59372955 creator A5055353781 @default.
• W59372955 creator A5063477062 @default.
• W59372955 date "2009-01-01" @default.
• W59372955 modified "2023-09-27" @default.
• W59372955 title "Ischemia-Reperfusion Induces ROS Production from Three Distinct Sources" @default.
• W59372955 cites W1498711742 @default.
• W59372955 cites W1675006565 @default.
• W59372955 cites W1971556924 @default.
• W59372955 cites W1972317764 @default.
• W59372955 cites W1983078193 @default.
• W59372955 cites W1983505595 @default.
• W59372955 cites W1988951836 @default.
• W59372955 cites W1990216374 @default.
• W59372955 cites W1999543531 @default.
• W59372955 cites W2006681786 @default.
• W59372955 cites W2013813451 @default.
• W59372955 cites W2018022526 @default.
• W59372955 cites W2032423144 @default.
• W59372955 cites W2041129027 @default.
• W59372955 cites W2041289197 @default.
• W59372955 cites W2055524735 @default.
• W59372955 cites W2057065995 @default.
• W59372955 cites W2068102230 @default.
• W59372955 cites W2072548356 @default.
• W59372955 cites W2080911031 @default.
• W59372955 cites W2081889973 @default.
• W59372955 cites W2086896843 @default.
• W59372955 cites W2088890601 @default.
• W59372955 cites W2096686378 @default.
• W59372955 cites W2113305005 @default.
• W59372955 cites W2121875633 @default.
• W59372955 cites W2152494586 @default.
• W59372955 cites W2170418680 @default.
• W59372955 cites W218003186 @default.
• W59372955 cites W4247088117 @default.
• W59372955 doi "https://doi.org/10.1007/978-1-60327-342-8_6" @default.
• W59372955 hasPublicationYear "2009" @default.
• W59372955 type Work @default.
• W59372955 sameAs 59372955 @default.
• W59372955 citedByCount "0" @default.
• W59372955 crossrefType "book-chapter" @default.
• W59372955 hasAuthorship W59372955A5055353781 @default.
• W59372955 hasAuthorship W59372955A5063477062 @default.
• W59372955 hasConcept C126322002 @default.
• W59372955 hasConcept C127413603 @default.
• W59372955 hasConcept C148762608 @default.
• W59372955 hasConcept C164705383 @default.
• W59372955 hasConcept C169760540 @default.
• W59372955 hasConcept C178790620 @default.
• W59372955 hasConcept C181199279 @default.
• W59372955 hasConcept C185592680 @default.
• W59372955 hasConcept C2778102346 @default.
• W59372955 hasConcept C2779134260 @default.
• W59372955 hasConcept C2780114680 @default.
• W59372955 hasConcept C2780130745 @default.
• W59372955 hasConcept C2780645631 @default.
• W59372955 hasConcept C2780795997 @default.
• W59372955 hasConcept C48349386 @default.
• W59372955 hasConcept C540031477 @default.
• W59372955 hasConcept C541997718 @default.
• W59372955 hasConcept C55493867 @default.
• W59372955 hasConcept C71924100 @default.
• W59372955 hasConcept C7836513 @default.
• W59372955 hasConcept C78519656 @default.
• W59372955 hasConcept C86803240 @default.
• W59372955 hasConcept C95444343 @default.
• W59372955 hasConceptScore W59372955C126322002 @default.
• W59372955 hasConceptScore W59372955C127413603 @default.
• W59372955 hasConceptScore W59372955C148762608 @default.
• W59372955 hasConceptScore W59372955C164705383 @default.
• W59372955 hasConceptScore W59372955C169760540 @default.
• W59372955 hasConceptScore W59372955C178790620 @default.
• W59372955 hasConceptScore W59372955C181199279 @default.
• W59372955 hasConceptScore W59372955C185592680 @default.
• W59372955 hasConceptScore W59372955C2778102346 @default.
• W59372955 hasConceptScore W59372955C2779134260 @default.
• W59372955 hasConceptScore W59372955C2780114680 @default.
• W59372955 hasConceptScore W59372955C2780130745 @default.
• W59372955 hasConceptScore W59372955C2780645631 @default.
• W59372955 hasConceptScore W59372955C2780795997 @default.
• W59372955 hasConceptScore W59372955C48349386 @default.
• W59372955 hasConceptScore W59372955C540031477 @default.
• W59372955 hasConceptScore W59372955C541997718 @default.
• W59372955 hasConceptScore W59372955C55493867 @default.
• W59372955 hasConceptScore W59372955C71924100 @default.
• W59372955 hasConceptScore W59372955C7836513 @default.
• W59372955 hasConceptScore W59372955C78519656 @default.
• W59372955 hasConceptScore W59372955C86803240 @default.
• W59372955 hasConceptScore W59372955C95444343 @default.
• W59372955 hasLocation W593729551 @default.
• W59372955 hasOpenAccess W59372955 @default.
• W59372955 hasPrimaryLocation W593729551 @default.
• W59372955 hasRelatedWork W1934035581 @default.
• W59372955 hasRelatedWork W2004646581 @default.
• W59372955 hasRelatedWork W2015562111 @default.
• W59372955 hasRelatedWork W2027250924 @default.

• next