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- W59457951 abstract "This chapter reviews studies on the pharmacology of aggression published over the past two to three years. It is noteworthy that problems with aggressive behaviour span diagnostic categories and that it is essential to emphasize that aggression covers a wide range of behaviours, which in very basic ways, serve both individual and species survival. Consequently only maladaptive or pathological aggressive behaviour is an appropriate target for pharmacotherapy. Neurochemical studies in animals suggest that cholinergic and catecholaminergic mechanisms are involved in the induction and enhancement of predatory or instrumental aggression while serotonergic and gamma amino butyric acid-ergic mechanisms are inhibitory. In affective aggression, dopaminergic mechanisms are facilitatory while noradrenergic and serotonergic mechanisms are inhibitory. These findings have still not led to a completely rational anti-aggressive pharmacopeia.KeywordsPersonality DisorderTemporal Lobe EpilepsySexual OffenderAntisocial Personality DisorderBorderline Personality DisorderThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
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- W59457951 date "1987-01-01" @default.
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- W59457951 title "Psychopharmacology of Aggression in Humans" @default.
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- W59457951 doi "https://doi.org/10.1007/978-94-009-3359-0_16" @default.
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