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- W595620032 endingPage "159" @default.
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- W595620032 abstract "The pancreatic hormone glucagon, well known essentially for its metabolic effects, has also been used as a pharmacologic tool in different conditions: as a provocative test for pheochromocytoma, as a stimulus for growth hormone release, in the treatment of uncomplicated insulin-induced and sulfonylurea-induced hypoglycemia, and in some cases of acute heart failure in which myocardial tissue is essentially healthy. From a chemical point of view glucagon is a member of the so-called secretin family and it shares 14 positionally identical amino acids with secretin (see Table 1 in Chap. 2a, Secretin), suggesting that these two peptides may have a common ancestral gene and that their structure may contain a still undeciphered message of phylogenetic and physiologic significance (for reviews see Lefebvre and Unger 1972; Foa et al. 1977). No wonder that their effects have so many points in common: both stimulate the secretion of insulin, inhibit gastric secretion, and exert a predominant inhibitory effect on gastrointestinal motility. This latter effect will be described in detail." @default.
- W595620032 created "2016-06-24" @default.
- W595620032 creator A5046369041 @default.
- W595620032 date "1982-01-01" @default.
- W595620032 modified "2023-09-27" @default.
- W595620032 title "Peptides: Pancreatic Hormones" @default.
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- W595620032 doi "https://doi.org/10.1007/978-3-642-68474-6_4" @default.
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