Matches in SemOpenAlex for { <https://semopenalex.org/work/W597370541> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W597370541 abstract "Background: Time to angiographic reperfusion has been hailed as paramount to all other factors in achieving good clinical outcomes after endovascular stroke therapy (EVT). Heterogeneity in collateral status, however, may dictate the individual timecourse of therapeutic risk/benefit in a given patient. Time to earliest reperfusion (Thrombolysis in Cerebral Ischemia 2A or TICI2A) has not been previously analyzed and this measure may considerably decrease with recent use of modern stentriever devices. Methods: ENDOSTROKE is an industry-independent, centrally-monitored multicenter registry evaluating EVT in routine clinical practice. Central reading of angiographic data blinded to clinical information was performed by the core lab. For these analyses, we selected only proximal MCA occlusions proven as TICI 0 before EVT, with available ASITN collateral grade and final TICI 2B-3. The data center analyzed the relationship of these angiographic parameters with clinical variables, including 90-day mRS 0-2 (good clinical outcome). Results: 116 patients met these strict inclusion criteria. Median age was 72 years (63, 76) with median initial NIHSS 15 (12, 19). 80 had good collaterals (ASTIN grades 3-4), 36 patients had poor collaterals (ASITN grades 0-2). Both groups did not differ significantly concerning age or initial NIHSS. Good clinical outcome was reached by 51% with good and 42% with poor collaterals (p=0.339). Time from symptom onset to the start of angiography was similar in both groups (200 min vs. 186 min in good vs. poor collaterals, p=0.393). However, in the poor collaterals group, time to TICI 2A was significantly shorter in patients with good clinical outcome (177 min (151, 221)) than in patients with poor clinical outcome (261 min (184, 326), p=0.012). In patients with good collaterals, no significant difference of the time to TICI 2A was found between good (229 min (152, 281)) and poor outcome (230 min (178, 298), p=0.779). Conclusions: Time to angiographic reperfusion, from symptom onset to earliest reperfusion (TICI 2A) dominates endovascular procedure time. Time is paramount in those with poor collaterals, whereas time may be irrelevant in those with good collaterals." @default.
- W597370541 created "2016-06-24" @default.
- W597370541 creator A5006310853 @default.
- W597370541 creator A5021425597 @default.
- W597370541 creator A5022489433 @default.
- W597370541 creator A5022523928 @default.
- W597370541 creator A5022823811 @default.
- W597370541 creator A5022948027 @default.
- W597370541 creator A5023593253 @default.
- W597370541 creator A5027244717 @default.
- W597370541 creator A5032082417 @default.
- W597370541 creator A5034245477 @default.
- W597370541 creator A5037999512 @default.
- W597370541 creator A5042438173 @default.
- W597370541 creator A5055812661 @default.
- W597370541 creator A5063248161 @default.
- W597370541 creator A5073114075 @default.
- W597370541 creator A5074466778 @default.
- W597370541 creator A5079518002 @default.
- W597370541 creator A5088314923 @default.
- W597370541 date "2015-02-01" @default.
- W597370541 modified "2023-10-02" @default.
- W597370541 title "Abstract W MP1: Collateral Grade Drives the Importance of Time to Reperfusion in the Stentriever Era: The ENDOSTROKE Registry" @default.
- W597370541 doi "https://doi.org/10.1161/str.46.suppl_1.wmp1" @default.
- W597370541 hasPublicationYear "2015" @default.
- W597370541 type Work @default.
- W597370541 sameAs 597370541 @default.
- W597370541 citedByCount "0" @default.
- W597370541 crossrefType "journal-article" @default.
- W597370541 hasAuthorship W597370541A5006310853 @default.
- W597370541 hasAuthorship W597370541A5021425597 @default.
- W597370541 hasAuthorship W597370541A5022489433 @default.
- W597370541 hasAuthorship W597370541A5022523928 @default.
- W597370541 hasAuthorship W597370541A5022823811 @default.
- W597370541 hasAuthorship W597370541A5022948027 @default.
- W597370541 hasAuthorship W597370541A5023593253 @default.
- W597370541 hasAuthorship W597370541A5027244717 @default.
- W597370541 hasAuthorship W597370541A5032082417 @default.
- W597370541 hasAuthorship W597370541A5034245477 @default.
- W597370541 hasAuthorship W597370541A5037999512 @default.
- W597370541 hasAuthorship W597370541A5042438173 @default.
- W597370541 hasAuthorship W597370541A5055812661 @default.
- W597370541 hasAuthorship W597370541A5063248161 @default.
- W597370541 hasAuthorship W597370541A5073114075 @default.
- W597370541 hasAuthorship W597370541A5074466778 @default.
- W597370541 hasAuthorship W597370541A5079518002 @default.
- W597370541 hasAuthorship W597370541A5088314923 @default.
- W597370541 hasConcept C126322002 @default.
- W597370541 hasConcept C126838900 @default.
- W597370541 hasConcept C127413603 @default.
- W597370541 hasConcept C141071460 @default.
- W597370541 hasConcept C164705383 @default.
- W597370541 hasConcept C2776599846 @default.
- W597370541 hasConcept C2779581417 @default.
- W597370541 hasConcept C2780643987 @default.
- W597370541 hasConcept C2780645631 @default.
- W597370541 hasConcept C500558357 @default.
- W597370541 hasConcept C71924100 @default.
- W597370541 hasConcept C78519656 @default.
- W597370541 hasConceptScore W597370541C126322002 @default.
- W597370541 hasConceptScore W597370541C126838900 @default.
- W597370541 hasConceptScore W597370541C127413603 @default.
- W597370541 hasConceptScore W597370541C141071460 @default.
- W597370541 hasConceptScore W597370541C164705383 @default.
- W597370541 hasConceptScore W597370541C2776599846 @default.
- W597370541 hasConceptScore W597370541C2779581417 @default.
- W597370541 hasConceptScore W597370541C2780643987 @default.
- W597370541 hasConceptScore W597370541C2780645631 @default.
- W597370541 hasConceptScore W597370541C500558357 @default.
- W597370541 hasConceptScore W597370541C71924100 @default.
- W597370541 hasConceptScore W597370541C78519656 @default.
- W597370541 hasIssue "suppl_1" @default.
- W597370541 hasLocation W5973705411 @default.
- W597370541 hasOpenAccess W597370541 @default.
- W597370541 hasPrimaryLocation W5973705411 @default.
- W597370541 hasRelatedWork W1561444587 @default.
- W597370541 hasRelatedWork W1592461968 @default.
- W597370541 hasRelatedWork W1969249790 @default.
- W597370541 hasRelatedWork W2035733943 @default.
- W597370541 hasRelatedWork W2054528597 @default.
- W597370541 hasRelatedWork W2093770497 @default.
- W597370541 hasRelatedWork W2189297481 @default.
- W597370541 hasRelatedWork W2200583486 @default.
- W597370541 hasRelatedWork W2282292770 @default.
- W597370541 hasRelatedWork W2288182794 @default.
- W597370541 hasRelatedWork W2326655283 @default.
- W597370541 hasRelatedWork W2567944563 @default.
- W597370541 hasRelatedWork W2570087714 @default.
- W597370541 hasRelatedWork W2591786826 @default.
- W597370541 hasRelatedWork W2761234326 @default.
- W597370541 hasRelatedWork W2763810102 @default.
- W597370541 hasRelatedWork W2917449908 @default.
- W597370541 hasRelatedWork W3010035802 @default.
- W597370541 hasRelatedWork W3030155637 @default.
- W597370541 hasRelatedWork W4226086112 @default.
- W597370541 hasVolume "46" @default.
- W597370541 isParatext "false" @default.
- W597370541 isRetracted "false" @default.
- W597370541 magId "597370541" @default.
- W597370541 workType "article" @default.