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- W59838892 abstract "580 Objectives Fibrous dysplasia of bone (FDB) reveals intense F-18 FDG uptake mimicking metastases on 18F-FDG PET-CT (Fig.). We reviewed sites of FDB revealed by 18F-FDG PET-CT imaging to allow identification of this abnormality. Methods Nine patients (6 m, 3 f, 16-73 y) were evaluated on a 16 slice MDCT whole-body PET scanner (Gemini, Philips), with LOR algorithm 3D reconstruction. Lesions were confirmed in five patients by biopsy. One and two hour imaging was performed after 0.14mCi/kg18F-FDG in eight patients. SUV for each lesion, on early and delayed imaging was calculated. The PET images were correlated carefully with MDCT to establish the imaging characteristics. Results Solitary lesions were found in three patients, the pubis and ilium in two, and in five multiple bone lesions. The SUVearly ranged from 1.23 to 5.26 with an average of 3.34±1.45. The SUVdelayed ranged from 1.76 to 7.21 with and average of 3.65±1.77. The SUVdelayed decreased or increased slightly in six of our patients, and increased significantly in two. There was a negative correlation between SUVearly and age, as well as between the number of affected bones and age. Conclusions In our study, FDB had wide skeletal distribution with variability of 18F-FDG uptake and CT appearance. SUV in the delayed stage was seen to either decrease or increase on dual-time 18F-FDG PET scanning. It is very important to recognize these characteristics of this skeletal dysplasia to allow differentiation from skeletal metastasis." @default.
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- W59838892 date "2009-05-01" @default.
- W59838892 modified "2023-09-23" @default.
- W59838892 title "Recognition of fibrous dysplasia of bone mimicking skeletal metastasis on 18F-FDG PET/CT imaging" @default.
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