Matches in SemOpenAlex for { <https://semopenalex.org/work/W600848024> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W600848024 abstract "When one is studying the physiology of the cutaneous microcirculation there is a need for relevant non-invasive and versatile techniques. In this study we used a new optical device, the tissue viability imager (TiVi), to map changes in cutaneous microvascular concentrations of red blood cells during iontophoresis of vasoactive substances (noradrenaline (NA) and phenylephrine (Phe) for vasoconstriction and acetylcholine (ACh) and sodium nitroprusside (SNP) for vasodilatation). We aimed to present data both individually and pooled, using a four-variable logistic dose response model that is commonly used in similar in vitro vascular studies. The accuracy of the TiVi was also investigated by calculating the coefficient of variation and comparing it with similar tests previously done using laser Doppler imaging. Tests were also performed using the TiVi and LDPI simultaneously to further compare the two methods. Results showed that the TiVi is capable of quantifying vascular responses to iontophorised noradrenaline and phenylephrine without the need to increase background flow first. Fitting the TiVi data to the dose response model resulted in ED50-values with narrow confidence intervals and acceptable r2 values. Mean ED50-values for the TiVi did not differ significantly from similar values obtained using laser Doppler. Results further seem to suggest that when the blood perfusion increases during vasodilatation in skin the initial phase relies mainly on an increase in red blood cell concentration whereas the further perfusion increase is due to an increase in red blood cell velocity." @default.
- W600848024 created "2016-06-24" @default.
- W600848024 creator A5059858312 @default.
- W600848024 date "2009-01-01" @default.
- W600848024 modified "2023-09-28" @default.
- W600848024 title "Assessment of microvascular effects of vasoactive drugs : Methodological in vivo studies in humansbased on iontophoresis" @default.
- W600848024 hasPublicationYear "2009" @default.
- W600848024 type Work @default.
- W600848024 sameAs 600848024 @default.
- W600848024 citedByCount "0" @default.
- W600848024 crossrefType "journal-article" @default.
- W600848024 hasAuthorship W600848024A5059858312 @default.
- W600848024 hasConcept C120770815 @default.
- W600848024 hasConcept C126322002 @default.
- W600848024 hasConcept C126838900 @default.
- W600848024 hasConcept C12722491 @default.
- W600848024 hasConcept C133828647 @default.
- W600848024 hasConcept C146957229 @default.
- W600848024 hasConcept C150903083 @default.
- W600848024 hasConcept C158846371 @default.
- W600848024 hasConcept C164705383 @default.
- W600848024 hasConcept C183529106 @default.
- W600848024 hasConcept C207001950 @default.
- W600848024 hasConcept C2777952589 @default.
- W600848024 hasConcept C2779610285 @default.
- W600848024 hasConcept C2779961880 @default.
- W600848024 hasConcept C42219234 @default.
- W600848024 hasConcept C519581460 @default.
- W600848024 hasConcept C52305850 @default.
- W600848024 hasConcept C71924100 @default.
- W600848024 hasConcept C84393581 @default.
- W600848024 hasConcept C86803240 @default.
- W600848024 hasConceptScore W600848024C120770815 @default.
- W600848024 hasConceptScore W600848024C126322002 @default.
- W600848024 hasConceptScore W600848024C126838900 @default.
- W600848024 hasConceptScore W600848024C12722491 @default.
- W600848024 hasConceptScore W600848024C133828647 @default.
- W600848024 hasConceptScore W600848024C146957229 @default.
- W600848024 hasConceptScore W600848024C150903083 @default.
- W600848024 hasConceptScore W600848024C158846371 @default.
- W600848024 hasConceptScore W600848024C164705383 @default.
- W600848024 hasConceptScore W600848024C183529106 @default.
- W600848024 hasConceptScore W600848024C207001950 @default.
- W600848024 hasConceptScore W600848024C2777952589 @default.
- W600848024 hasConceptScore W600848024C2779610285 @default.
- W600848024 hasConceptScore W600848024C2779961880 @default.
- W600848024 hasConceptScore W600848024C42219234 @default.
- W600848024 hasConceptScore W600848024C519581460 @default.
- W600848024 hasConceptScore W600848024C52305850 @default.
- W600848024 hasConceptScore W600848024C71924100 @default.
- W600848024 hasConceptScore W600848024C84393581 @default.
- W600848024 hasConceptScore W600848024C86803240 @default.
- W600848024 hasLocation W6008480241 @default.
- W600848024 hasOpenAccess W600848024 @default.
- W600848024 hasPrimaryLocation W6008480241 @default.
- W600848024 hasRelatedWork W1476003443 @default.
- W600848024 hasRelatedWork W1592920810 @default.
- W600848024 hasRelatedWork W1969429157 @default.
- W600848024 hasRelatedWork W1972106134 @default.
- W600848024 hasRelatedWork W1977083740 @default.
- W600848024 hasRelatedWork W1985877174 @default.
- W600848024 hasRelatedWork W1991590982 @default.
- W600848024 hasRelatedWork W2018262275 @default.
- W600848024 hasRelatedWork W2038757280 @default.
- W600848024 hasRelatedWork W2040458434 @default.
- W600848024 hasRelatedWork W2043648228 @default.
- W600848024 hasRelatedWork W2067569137 @default.
- W600848024 hasRelatedWork W2092490969 @default.
- W600848024 hasRelatedWork W2101016625 @default.
- W600848024 hasRelatedWork W216651141 @default.
- W600848024 hasRelatedWork W2349778574 @default.
- W600848024 hasRelatedWork W3009839151 @default.
- W600848024 hasRelatedWork W3113514354 @default.
- W600848024 hasRelatedWork W323568175 @default.
- W600848024 hasRelatedWork W1778773267 @default.
- W600848024 isParatext "false" @default.
- W600848024 isRetracted "false" @default.
- W600848024 magId "600848024" @default.
- W600848024 workType "article" @default.